news PARK14 protein associated with inflammation in Parkinson’s 15 March 2018 | By Dr Zara Kassam (Drug Target Review) Study overturns previous ideas about enzyme linked to many illnesses
news Turning off autophagy helps chemotherapy stress cancer cells to death 14 March 2018 | By Drug Target Review A study has pinpointed a molecule that links autophagy and apoptosis, namely a transcription factor called FOXO3a.
news Modified PIP protein differentiates between cancerous and non-cancerous cells 13 March 2018 | By Dr Zara Kassam (Drug Target Review) A discovery sheds light on how cancerous cells differ from healthy ones and could lead to the development of new strategies for therapeutic intervention for difficult-to-treat cancers...
news EGFL7 protein provides a new treatment approach for MS 7 March 2018 | By Dr Zara Kassam (Drug Target Review) Researchers have discovered that the EGFL7 protein inhibits the migration of immune cells into the brain...
news Blockade of MT4-MMP protease increases blood-patrolling monocyte activity 6 March 2018 | By Drug Target Review Researchers in Spain have identified a function of the MT4-MMP protease (an enzyme that breaks down proteins) that could be targeted as a potential treatment for some infections, as well as tumour metastasis.
news Scientists create complex transmembrane proteins from scratch 5 March 2018 | By Dr Zara Kassam (Drug Target Review) Advance paves the way for the design of transmembrane proteins with useful new functions...
news Researchers evaluate tau phosphorylation related targets for Alzheimer’s research 1 March 2018 | By Drug Target Review Scientists in Moscow have extended the reach of QSP modelling by applying it to tau phosphorylation to better understand Alzheimer’s disease (AD) progression.
news HIC1 protein may protect against intestinal disease 26 February 2018 | By Dr Zara Kassam (Drug Target Review) Scientists find molecular link between Vitamin A derivative and mouse intestinal health...
news Scientists halt breast cancer spread 9 February 2018 | By Drug Target Review Scientists have discovered that the amino acid asparagine is essential for breast cancer spread, and by restricting it, cancer cells stopped invading other parts of the body in mice.
news LiP-mass spectrometric analysis measures molecular interactions 2 February 2018 | By Dr Zara Kassam (Drug Target Review) Researchers have systematically analysed and quantified the interactions of all proteins with metabolites on the level of the whole proteome...
news TIMP-1 protein plays role in reducing cancer’s spread 31 January 2018 | By Dr Zara Kassam (Drug Target Review) Researchers have found that the TIMP-1 molecule that helps regulate gene expression plays a big role in keeping us safe from the machinations of cancer...
news Alpha-4 beta-7 protein levels linked to HIV infection risk 31 January 2018 | By Dr Zara Kassam (Drug Target Review) Scientists have shown a relationship between the proportion of key immune cells that display high levels of alpha-4 beta-7 at the time of HIV infection and health outcomes...
news MSK1 protein keeps metastatic breast cancer cells dormant 25 January 2018 | By Dr Zara Kassam (Drug Target Review) A study has identified the genes involved in the latent asymptomatic state of breast cancer metastases...
news HIF-1 protein shows promise as a non-hormonal treatment for menorrhagia 24 January 2018 | By Dr Zara Kassam (Drug Target Review) Researchers have identified a key protein that could explain why heavy bleeding occurs during menorrhagia, paving the way for potential treatments that avoid the need to take hormones...
news G-CSF protein involved in cocaine addiction 18 January 2018 | By Dr Zara Kassam (Drug Target Review) Researchers have identified a protein produced by the immune system that could be responsible for the development of cocaine addiction...
