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The emergence of targeted alpha therapy for glioblastoma
Targeted alpha therapy shows promising preclinical results, increasing survival rate by 36.4 percent in recurrent tumours.
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Radiotherapy
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New 3D genomic profiling technique details PanINs
Researchers have developed a 3D approach to improve the characterisation of pancreatic intraepithelial neoplasias.
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Intratumoural bacteria drives radiation therapy resistance
Lactate producing bacteria is responsible for rewiring metabolic signalling pathways, causing resistance to radiation therapy.
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Combination therapy effective against canine melanoma
A combination of radiotherapy followed by immunotherapy is a promising strategy for the treatment of oral malignant melanomas in dogs.
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Scientists identify therapeutic targets to overcome radioresistance of brain cancer cells
A new drug could replace the current standard for treating radioresistance brain cancer by sensitising the cancer cells to radiotherapy.
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Nanotechnology: a new immuno-onocology weapon
This article outlines three innovative studies that use nanotechnology to deliver a new immunotherapy approach towards cancers.
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Discovered receptor that could alleviate the need for chemotherapy
Researchers have shown that a synthetic IL-9 receptor allows T cells to fight against cancer without the need for chemotherapy or radiation.
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New combinatorial strategies to treat ovarian cancer
Researchers have found how ovarian cancer tumours defy immunotherapy, identifying new molecular targets that might boost immune response.
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New potential therapy developed in response to bladder cancer
Research in mice has shown that adding anti-inflammatory medication to immunotherapy and standard chemotherapy drugs may provide long-term suppression of aggressive bladder tumour growth.
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Wyss Centre initiates collaboration to improve brain tumour treatment
The Wyss Centre has announced a collaborative project to improve understanding of the brain cancer glioblastoma and develop new personalised therapies.
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IL13Ra2 revealed as target against breast cancer-related brain metastasis
Interleukin 13 receptor alpha 2 was found in increased rates in cancer cells that metastasised to the brain and lungs, a new study has shown.
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Drug could prevent cognitive decline associated with brain tumour radiation
Researchers demonstrated NSPP completely prevented cognitive decline in mice treated with radiation for patient-derived glioblastomas.
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MLL gene key to producing hematopoietic stem cells, says research
Researchers investigating childhood leukaemia have discovered that increasing MLL gene expression in iPSCs drives hematopoietic stem cell production, so could be the target of new therapies.
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GC4419 could prevent debilitating side effect of cancer treatment
Researchers are reporting on a new drug that can treat the painful and debilitating side effect of severe oral mucositis (SOM)...
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Cancer drug screening: the historical perspective
Chemotherapy with cytotoxic and growth inhibitory drugs have played an important role in cancer therapy, used either alone or in combination with other treatment modalities such as surgery, radiation or biological therapy. Chemotherapy, in most instances, was the only alternative treatment for metastatic cancer – mainly given as drug combinations...