news
Breakthrough made in herpes antiviral molecule development
Researchers have created a new method of potentially treating herpes virus, by targeting the physical properties of the viral genome.
List view / Grid view
Research & Development
news
Team redesigns COVID-19 Spike protein for more stable vaccines
Researchers have modified the COVID-19 Spike protein for use in vaccines, which produces up to 10 times more protein than that of an earlier synthetic versions.
news
Chloroquine does not prevent SARS-CoV-2 infection in human lung cells, study finds
A new study has shown that while chloroquine protects African green monkey kidney cells from SARS-CoV-2 infection, it does not protect human lung cells.
news
Researchers develop potential drug to prevent heart attacks
A novel drug has been created which prevented the blood clotting associated with heart attacks and strokes in pre-clinical studies.
article
Five of the most recent microscopy developments
Drug Target Review highlights five of the latest imaging advancements in the field of microscopy.
news
Nanoparticle COVID-19 vaccine elicits immune response in pre-clinical studies
The vaccine candidate repRNA-CoV2S elicited both antibody and T cell responses after just two injections in mice and macaques.
news
Most antibodies targeting SARS-CoV-2 use specific immunoglobulin subtype
Researchers reveal IgHV3-53 is the most common immunoglobulin mutation used to target the receptor binding domain on the SARS-CoV-2 spike protein.
article
Drug side effects: an open source tool to predict adverse reactions
Researchers who developed a machine learning algorithm to predict the adverse effects of new drug compounds have released it as an open source tool.
news
Novel bioactive dialysis system improves survival in pigs with acute liver failure
The bioreactor-based system incorporates liver cells to perform the detoxifying functions of the liver and was tested on pigs with acute liver failure.
article
Prophylactics for COVID-19 – known and unknown
This article outlines the ideal scientific research that should be conducted to design a prophylactic to combat COVID-19.
news
Developing a nanoparticle-delivered gene therapy for blinding eye disease
Ophthalmology and engineering combine in a novel nanoparticle-delivered gene therapy approach to treating wet age-related macular degeneration.
article
The hope of rejuvenation: using plasma to reverse ageing in mice
Researchers have found that a plasma exchange process can act as a molecular reset button for old blood, improving the health of ageing mice.
news
Genomics England launches next-generation research platform
The genomic research platform will initially be used to help fast-track COVID-19 drug research and development, before being leveraged against other diseases, such as cancer.
news
Novel vitamin K analogue eliminates seizure activity in epileptic mouse models
The vitamin K-based drug has a unique structure which researchers believe makes it effective in controlling even medication-resistant seizures.
news
Novel class of non-addictive analgesics demonstrate safety in animals
To overcome the issues of current analgesics, researchers reveal a new class of non-narcotic pipeline drugs based on acetaminophen.