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Combination of two neutralising antibodies suggested as COVID-19 treatment
Two antibodies named B38 and H4 could work as a COVID-19 therapeutic by neutralising the virus, say researchers in China.
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Research & Development
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Results from first epigenetic study in 3D human cancer cells published
A new paper describes the first full study of the epigenetics of human tumour organoids, suggesting this could be used to develop novel oncology treatments.
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Utilising an interleukin-12 plasmid: a novel COVID-19 vaccine
Dr Bernard Fox from Providence Cancer Institute explains how OncoSec’s CORVax12 vaccine works to potentially combat COVID-19.
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Blueprint for adapting US labs for COVID-19 diagnostic testing
Researchers in Boston have repurposed their lab into a centre to test samples for COVID-19, releasing a blueprint of how to do so for other labs in the US.
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Free to use COVID-19 Protein Portal launched for researchers in UK
The COVID-19 Protein Portal, established by UKRI and Wellcome, will allow scientists in the UK to access protein reagents needed for research.
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Procedure developed to create murine models of COVID-19 for testing of therapeutics and vaccines
Russian researchers have created a process for the development of mouse models for use in pre-clinical studies of COVID-19 treatments and vaccines.
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New class of antigen-presenting immune cell identified by researchers
A new kind of dendritic cell has been discovered by researchers and could play a role presenting antigens to other immune cells during respiratory virus infections.
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Molecules derived from ticks could be used as late-stage COVID-19 treatment
Researchers have found that molecules from ticks called Evasins have the potential to halt cytokine storms, the leading cause of COVID-19 fatalities.
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Chromatography and bioassays used to detect bioactive compounds in plants
Bioassays and thin-layer chromatography has been used by scientists to analyse molecules in plant extracts as a fast and cost-effective method for identifying new drug compounds.
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Researchers develop promising MERS vaccine, with potential for COVID-19
A MERS vaccine, which uses RNA-based adjuvants, has demonstrated efficacy in non-human primates and is now being developed as a prophylactic for COVID-19.
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L1 compound identified as potential treatment for Alzheimer’s disease
A new compound named L1 has demonstrated success in mice, by reducing neuroinflammation and decreasing the levels of amyloid plaques, showing potential as an Alzheimer's treatment.
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Multivalent carbohydrate-binding modules show efficacy against COVID-19
Tested on plaque reducing assays, researchers have identified a lead candidate multivalent carbohydrate-binding module for the treatment of COVID-19.
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Structure of SARS-CoV-2 suggests reason for high infection rate, says study
Researchers have identified a structural loop in the SARS-CoV-2 S protein and a sequence of four amino acids that they say could help explain its high transmission rate.
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LAL assay derived from aquaculture could be used to detect endotoxins in human blood
Tests have shown that LAL assays produced from L. polyphemus in aquaculture often has a higher activity than lyophilised and preserved LAL from commercial kits.
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Researchers analyse SARS-CoV-2 genome, identifying 198 mutations
After analysing the genomic diversity in SARS-CoV-2 by screening over 7,500 viruses from infected patients, researchers have offered clues for COVID-19 drug development.