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YAP protein identified as new target for Alzheimer’s disease
Researchers have discovered that neuronal necrosis occurs in Alzheimer's earlier than previously though and revealed the YAP protein as a potential target.
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Increasing NAD levels could improve quality of eggs, says research
A study has identified that infertility due to age-related defects in eggs could be improved by raising levels of NAD, presenting a possible novel fertility treatment.
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ELRIG and the British Pharmacological Society: why form a strategic alliance?
Here, the benefits of collaborating in drug discovery are explored through the strategic alliance between ELRIG and the British Pharmacological Society.
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Murine model for coeliac disease may lead to future therapies, say researchers
Using an innovative approach to create a model organism, scientists have translated human research into a murine model which they say more accurately reflects coeliac disease.
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Class of antibiotics with unique mechanism to combat bacteria discovered
Researchers have uncovered new antibiotics which prevent bacteria from multiplying, offering a strategy to fight infections.
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CRISPR ‘minigene’ used to prevent genetic liver disease in mice
Researchers have developed a new CRISPR technique, using a minigene, which was inserted into mouse DNA, resulting in improved liver disease symptoms.
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Carbon hydrogen functionalisation could provide new route for synthesising compounds
The carbon hydrogen functionalisation process could be used to make 3D scaffolds for pharmaceutical compounds, say researchers.
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Free radicals from immune cells cause salt-sensitive hypertension
A new study has found that in salt-sensitive hypertension, immune cells gather and release free radicals, damaging the kidneys.
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3D printing ‘bio-ink’ developed for regenerative medicine
Using modified hyaluronic acid and polyethylene glycol, researchers have created a bio-ink for 3D printing, which could be used as a scaffold to grow human tissues.
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The fate of cancer is all down to particular proteins
Scientists in Japan have identified an important protein that can impact the course of cancer and its fate in the human body.
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Novel label-free method enables imaging of metabolites
A label-free imaging technology has been developed by researchers, allowing them to investigate biomolecules such as metabolites, aiding in the study of drugs.
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CD229 CAR T-cell therapy treated tumours had lasting response mice
Researchers have created a CAR T-cell therapy which targets the CD229 molecule expressed on all multiple myeloma cells and killed human tumour cells in mice.
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Gene editing platform improves vision in blind mice
Mice with congenital blindness have shown significant improvement in vision after undergoing a new gene therapy.
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G-1 compound could be used to fight obesity and diabetes
Studies in mice have shown that the G-1 compound reduces obesity and the effects of diabetes by burning extra calories, report researchers.
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Report finds £4.8m of funding contributed to UK health research in 2018
Researchers have found that half of public and charity support for health research over the past 14 years has been for studying the cause and progression of disease.