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Therapeutic RNA corrects splicing defect that causes familial dysautonomia
Scientists have identified a therapeutic RNA molecule that corrects the error in genetic processing that leads to familial dysautonomia...
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webinar
in vitro phenotypic assays for Parkinson’s disease
26 April 2018 | By Charles River Laboratories
This webinar highlights cell based assays for Parkinson’s disease that include endpoints such as a-synuclein aggregation and mitophagy readouts.
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Man-made antibodies show promise in attacking cancer cells in animal models
Molecules called aptamers could form new, safer chemotherapy delivery systems...
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RNA-based therapy targets West Nile virus
A research team has developed a new RNA therapy, delivered through the nose, to treat mice infected with West Nile Virus...
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MAPseq technique provides new blueprint for cortical connections
Using a revolutionary new brain-mapping technology will force neuroscientists to rethink how areas of the cortex communicate with one another...
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NAMD software brings subatomic resolution to computational microscope
Scientists have built a computational microscope that can simulate the atomic and subatomic forces that drive molecular interactions...
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MVP found to be consequential in 16p11.2 deletion syndrome
Neuroscientists have identified a specific molecular mechanism that appears to undermine the ability of neurons to properly incorporate changes driven by experience...
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miRNAs of abnormal heart rhythms identified in circulating blood
Researchers uncover four microRNA molecules in the bloodstream that could predict the onset of atrial fibrillation...
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Splicing-variant detection method identifies biomarkers for HCC
Researchers report a method for identifying splicing-based biomarkers for hepatocellular carcinoma....
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Scientists discover critical molecular biomarkers of preeclampsia
Small non-coding RNAs may be used to devise a diagnostic blood test for pregnant women...
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CRISPR/Cas9 variant holds promise for Huntington’s disease treatment
Improvements to gene-editing techniques hold promise for inactivating the defective gene responsible for this as-yet incurable disease...
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Single-cell RNA sequencing provides molecular atlas to study brain diseases
Researchers have detailed a molecular atlas of the cells that form the brain's blood vessels and the life-essential blood-brain barrier providing clues to which cell types are involved in different diseases...
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Huntington’s disease provides new cancer weapon
Scientists have discovered why Huntington's is so toxic to cancer cells and harnessed it for a novel approach to treat cancer...
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SMi’s 9th annual RNA Therapeutics conference will take place in just 2 weeks!
Presenting issues and real-life examples within the RNA space, SMi welcome insights and discussions into new technologies for single-stranded RNA, epigenetics to develop first-in class drugs in oncology, patenting RNA Therapeutics and exploring the latest developments in delivery systems, including Exosomes and Nanocomplexes. Read on for your exclusive discount to…
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Scientists uncover the secret to how piRNAs defend the genome
Researchers from the University of Chicago have uncovered the mechanism by which small RNA molecules (piRNAs) locate and silence foreign invading genes, whilst avoiding ‘self’ genes.