news
Predatory bacteria may be a potentially safe alternative to antibiotics
Researchers have identified tools that may allow for the manipulation of genes that influence bacteria’s predatory behaviour...
List view / Grid view
RNAs
news
Influenza viruses can help mutated viral proteins fold and function
A new study from has shed light on just how viruses evolve so quickly and offers a potential way to slow them down...
news
RNA cells genetically re-programmed to fight cancer
RNA cells can be genetically programmed like a computer to fight cancer, influenza, and other serious conditions...
news
Scientists discover new bacterial defence mechanism of CRISPR-Cas system
A team of researchers – headed by the University of Zurich – have discovered a new mechanism by which bacteria are protected from invading viruses and molecular parasites.
news
New study reveals new drug target for gout & inflammatory diseases
Research reveals cathepsins as potential therapeutic targets in particulate-mediated inflammatory disease…
news
Micro-gene protects the brain from developing epilepsy
A tiny microRNA has been shown to play a beneficial role in protecting the brain from epileptic seizures in specially engineered transgenic mice.
news
Using single-cell RNA sequencing to track stem cell development
Adult stem cells have the ability to transform into many types of cells, but tracing the path individual stem cells follow as they mature and identifying the molecules that trigger these fateful decisions are difficult in a living animal.
article
Towards systems biomarkers for cancer diagnosis
Cancer is asymptomatic during most of its pathogenesis. It is very difficult to see that a cancer is growing in a person, except for a few self-evident cases such as skin cancer. Its intangibility and year-, if not decade-long progression make cancer hard to diagnose until some symptoms warrant further…
news
Changes in RNA splicing: a new mechanism for genetic risk in schizophrenia
New research has identified sections of DNA associated with altered regulation of gene expression underlying schizophrenia.
webinar
Vertical integration of CRISPR/Cas9 in drug discovery
10 February 2017 | By Charles River
In this webinar, Charles River discuss the utilisation of CRISPR/Cas9 technology in drug discovery, with an emphasis on generation of in vitro models for high-throughput screening, and creating new mouse models...
article
Valid biomarker signatures from liquid biopsies – how to standardise NGS
The advent of next-generation sequencing (NGS) techniques has revolutionised transcriptomics research and opened numerous avenues for scientific and clinical applications. While reverse transcriptase quantitative real-time polymerase chain reaction (RT-qPCR) is still considered the gold standard of gene expression analysis, its high throughput, single-nucleotide resolution and ever-plummeting costs have made NGS…
news
Programmable RNA vaccines effective against Ebola and influenza
4 July 2016 | By Victoria White, Digital Content Producer
MIT engineers have developed easily customisable RNA vaccines that can be manufactured in one week and have shown efficacy against ebola and H1N1 influenza...
news
Storm Therapeutics secures £12 million in series A funding
28 June 2016 | By Victoria White, Digital Content Producer
Storm Therapeutics has secured £12 million in series A funding to identify small molecular drugs that target RNA-modifying enzymes...
article
The next revolution in stratified medicine: molecular phenotyping with metabolomics
The study of biochemistry provides molecular insights into how the human population ages, how diseases commence and progress, how molecular changes relate to disease remission and relapse, and how humans respond to treatments...