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Therapeutically effective drugs identified for bladder cancer
By screening various drugs, a new study has found a childhood leukaemia therapeutic is also efficient in treating bladder cancer.
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Screening
Medical screening is a strategy used to identify the possible presence of an as-yet-undiagnosed disease in individuals without signs or symptoms.
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Blocking host proteins: an improved COVID-19 treatment approach?
Scientists report news of a promising new compound that effectively blocks the activity of proteins on cells that are necessary for SARS-CoV-2 to cause infection.
webinar
An efficient and effective PIM3 kinase-focused screening cascade for identification of multiple novel and tractable hit series
14 April 2022 | By Eurofins Discovery Services
Watch this free on-demand webinar to understand how to rapidly identify selective, specific, potent and tractable hit series with appropriate ADME characteristics to speed up hit-to-lead.
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Under the microscope: Unveiling a next-generation imaging system with deep learning technology
The ImageXpress Confocal HT.ai High-Content Imaging System combines premium hardware technology with a self-learning software analysis workflow for increased signal and ultra-fast 3D organoid screening.
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Product hub: Scalable and automated 3D cell cultures for high-throughput and high-content screening
Read about hydrogels that provide defined and tuneable material properties that allow the controlled inclusion of biochemical cues.
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Bulletin: Utilising the multiparameter capability of the Ze5 Cell Analyser to monitor T cell exhaustion and effects of immunotherapy
Read this bulletin to learn about a Bio-Rad study where they developed and tested a 16-parameter flow cytometry panel applicable to the interrogation of a range of biologically relevant markers of T cell activation.
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Whitepaper: Advancing cardiac drug discovery with iPSC technology
A review of current challenges and goals in cardiac drug discovery and how innovations on human iPSC technology are helping to overcome them.
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Guide: How efficient is your lab? – Try this calculator
Do you know how much time your lab spends on pipetting tasks daily? If not you can easily find out. Just answer four simple questions, then Flow Robotics' calculator can give you a full report on how your lab is doing in minutes.
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Uniting industry and academia for phenotypic drug discovery
A collaboration between Exscientia and the University of Oxford Target Discovery Institute (Oxford TDI) has been established to source cellular functional assays from the global academic community, with the goal of developing novel screens and identifying targets and therapeutic candidates for unmet medical needs. Here, Dr Denise Barrault, Director of…
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Driving precision neurology forwards with iPSCs and new assays
Precision medicine in neurology is limited by a dearth of clinically relevant models. However, here Dr Evangelos Kiskinis, Assistant Professor at Northwestern University Feinberg School of Medicine, discusses how new technologies such as bioelectronic assays enable real-time, long-term analysis of neurological diseases in a dish, offering a pathway towards identifying…
news
New screening method reveals why Alzheimer’s drugs often fail
Researchers have developed a new method to screen drugs for Alzheimer’s disease, shedding light on why current drugs have failed and identifying novel drug targets.
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NanoTemper Technologies launches Spectral Shift, a breakthrough technology that changes the game for affinity-based screenings
NanoTemper Technologies has announced the launch of Spectral Shift technology with its Dianthus instrument.
webinar
timsTOF MALDI PharmaPulse, a trapped ion mobility-enabled mass spec solution for label-free HTS in drug discovery
25 March 2022 | By Bruker Daltonics
Watch our free on-demand webinar to discover how the new timsTOF MPP product solution, with its dedicated MALDI PharmaPulse 2023 HTS software suite, improves data quality and accelerates high-throughput screening in drug discovery.
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Cell painting approach used to identify drug compounds with unwanted side effects
Novel research has shown that morphological fingerprinting could help identify side effects of new bioactive compounds in drug discovery.
webinar
Image-based, quantitative approaches to study SARS-CoV-2 cell entry and infection: looking for the Achilles’ heel of virus infection
21 February 2022 | By Yokogawa Deutschland GmbH
Watch our free on-demand webinar to discover how fully automated imaging and image analysis can provide the unprecedented possibility to follow single viral particles, including for SARS-CoV-2.