news
Cell painting approach used to identify drug compounds with unwanted side effects
Novel research has shown that morphological fingerprinting could help identify side effects of new bioactive compounds in drug discovery.
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Screening
Medical screening is a strategy used to identify the possible presence of an as-yet-undiagnosed disease in individuals without signs or symptoms.
webinar
Image-based, quantitative approaches to study SARS-CoV-2 cell entry and infection: looking for the Achilles’ heel of virus infection
21 February 2022 | By Yokogawa Deutschland GmbH
Watch our free on-demand webinar to discover how fully automated imaging and image analysis can provide the unprecedented possibility to follow single viral particles, including for SARS-CoV-2.
news
Study identifies new therapeutic target for haematologic malignancies
Using chemical genetic screening and pre-clinical model studies, researchers have discovered that inducing ubiquitin-mediated degradation of mutant EZH2 could provide a more effective treatment strategy for haematologic malignancies.
news
Five SARS-CoV-2 antiviral candidates revealed in drug screening study
Using virtual screening, researchers have discovered several natural compounds that could inhibit the SARS-CoV-2 main protease.
whitepaper
Whitepaper: How to successfully use iPSCs for disease modelling
Benefits and key considerations of using human iPSC-derived disease models in drug discovery.
news
New photonic effect could accelerate drug screening processes
Researchers have shown that twisted nanoscale semiconductors can be utilised to accelerate the discovery of drugs through high-throughput screening.
whitepaper
Brochure: Automation drug discovery
Accelerate your drug discovery workflows efficiently and cost-effectively with lab automation solutions from Beckman Coulter Life Sciences.
podcasts
Episode 5 – Small molecule screening with Dr Sheraz Gul, Fraunhofer Institute & Dr John Fuller, Beckman Coulter
In this latest episode, we discuss how small molecule discovery can be automated and how this process saves researchers time and money.
news
Virtual method enables screening of billions of chemical compounds
A new platform, named Virtual Synthon Hierarchical Enumeration Screening, has been developed by researchers to efficiently discover drugs.
whitepaper
Product hub: High-content 3D confocal imaging of live cell clusters
Learn about the high-content analysis system that provides high-quality three-dimensional imaging for enhanced live cell analysis.
whitepaper
Application note: Cell line development: accelerating process optimisation
This study demonstrates the ease, simplicity and speed of performing multiple conditions in one experiment using Ambr 15 Cell Culture by assessing five different media compositions on two different clones.
webinar
Unlocking orphan GPCRs with an innovative forward trafficking approach
16 December 2021 | By Eurofins DiscoverX and Sanford Burnham Prebys Medical Discovery Institute
Watch this on-demand webinar to learn about orphan GPCRs as drug targets and the challenges related to lead identification.
news
New platform screens for specific class of coronavirus antiviral compounds
Researchers developed a platform that can rapidly screen thousands of compounds to identify potential antiviral drugs to treat coronaviruses.
news
“Overlooked” FAM72A gene shines light on antibody production
Scientists used a new screen to identify FAM72A as a cause of mutagenesis that affects antibody development in COVID-19 and cancer.
news
Single molecule from plant used by Native Americans may treat diarrhoea
Scientists unveil the role of KCNQ2/3 using a functional screen of 40 native US plants and identify nine extracts that could treat diarrhoea.