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Scientists use stem cells to generate rudimentary kidney organoids
Researchers have developed kidney organoids that resemble the collecting duct system, using ureteric bud progenitor cells.
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Screening
Medical screening is a strategy used to identify the possible presence of an as-yet-undiagnosed disease in individuals without signs or symptoms.
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Researchers 3D print rotating microfilter for lab-on-a-chip applications
A new magnetically driven rotary microfilter has been developed to filter particles inside a lab-on-a-chip microfluidic device.
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Drug Target Review – Issue 2 2021
This issue includes articles on novel AAV vectors to deliver ocular gene therapy, how phenotypic models of disease are being used in covalent fragment screening and the challenges and opportunities presented by automation in the life sciences. Also in this issue are features on stem cells, antibodies and hit-to-lead.
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Infographic: A custom monoclonal antibody for your next project
Learn what sets Bethyl custom monoclonal antibodies quality and service apart and discover the top reasons why you should choose Forits Life Sciences for your next project.
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Brochure: Neuroscience solutions
Complete solutions for neurological disease research and discovery - helping you to better understand diseases to improve patient outcomes.
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Study shows how novel drug screen can personalise cancer therapy
A screening method called dynamic BH3 profiling can identify potentially effective combinations of existing drugs for personalised cancer therapy, research has shown.
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Screening identifies existing drugs as potential COVID-19 therapies
Scientists have found four clinically approved drugs and nine compounds with the potential to be repurposed as therapeutics for COVID-19.
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ebook: How automation makes labs more efficient
We discuss how liquid handling automation supports drug discovery workflows & highlight opportunities to improve the efficiency and quality of these.
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High-throughput screening platform detects henipavirus antivirals
A new high-throughput screening platform has been used to identify two compounds with antiviral activity against the Nipah and Hendra viruses.
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Application note: Western blot & IP assay to verify antibody specificity
Learn about a practical, high-throughput method for validating the target-specificity of antibodies for the application of western blot.
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New immunosensor developed for use in immunoassays
A modified luciferase enzyme has been developed as an immunosensor to be fused with a Q-body and used in immunoassays.
webinar
Automating functional cell-based bioassays: assay reproducibility and performance for potency testing programmes
28 May 2021 | By Eurofins DiscoverX* and Tecan
In this on-demand webinar, we discuss how Eurofins DiscoverX’s off-the-shelf, MOA-based functional, cellular assays address these challenges, enabling drug discovery programmes up to late-stage development and market release.
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Brochure: Immuno-Oncology Solutions
A wide range of tools to support your immuno-oncology research and help redefine and develop tailored, life-changing immunotherapies to fight cancer.
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High-throughput screening assay developed to discover antimalarials
A new assay has been developed to screen for small molecule inhibitors of the Rh5 protein, which is essential for malaria parasite survival.
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How microfluidics can automate drug discovery and development
Researchers from the University of Minnesota have developed a 3D spherical microfluidic device. Here, Dr Ruitao Su explains how the new device can be used in drug discovery and development.