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Sequencing

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Complete DNA sequence of the X chromosome revealed

15 July 2020 | By Hannah Balfour (Drug Target Review)

Researchers capitalised on novel sequencing technologies to produce the first end-to-end DNA sequence of the X chromosome.

video

Video: ESHG 2019 conference discussion panel: automated sample preparation

10 June 2020 | By Thermo Fisher Scientfic

A result is only as good as the sample preparation that preceded it.

video

Video: Overview of the KingFisher^TM instruments

10 June 2020 | By Thermo Fisher Scientific

ESHG 2019: Automated sample preparation using magnetic bead technology and KingFisher instruments.

coronavirus particle in the crosshares with 'target locked' written above

news

Computational approach identifies novel COVID-19 vaccine targets

9 June 2020 | By Hannah Balfour (Drug Target Review)

Researchers used computational tools to identify regions of the SARS-CoV-2 virus that could potentially provide a safe and long-term immune response.

whitepaper

Application note: High-throughput pathogen detection using a novel MagMAX kit and OpenArray technology

9 June 2020 | By Thermo Fisher Scientfic

Automated detection and isolation of pathogens for multiple samples types.

video

Video: Isolate Circulating tumor cells using the KingFisher

9 June 2020 | By Thermo Fisher Scientfic

New opportunities for liquid biopsy: At automated workflow for isolating circulating tumor cells using KingFisher instruments.

whitepaper

Application note: Sensitive detection of viral nucleic acids

8 June 2020 | By Thermo Fisher Scientific

A simple and sensitive method for nucleic acid extraction from virus-containing samples, with a range of viral loads.

whitepaper

Application note: Metagenomic analysis of the human microbiome

8 June 2020 | By Thermo Fisher Scientfic

Isolate high-quality, inhibitor-free DNA and RNA from human stool and other sample types suitable for metagenomics sequencing.

article

Neoantigens: presenting new vaccine opportunities in immuno-oncology

4 June 2020 | By Nikki Withers (Drug Target Review)

Neoantigens have gained much interest in recent years, mainly due to their ability to elicit a strong, specific immune response. Nikki Withers spoke to two immunology experts to explore the progress being made and assess what remains challenging for cancer investigators working on these transformational therapies.

whitepaper

ebook: How to start your own lab

26 May 2020 | By NanoTemper Technologies

Learn practical tips from eight Principal Investigators about how to start your own lab.

news

Structure of SARS-CoV-2 suggests reason for high infection rate, says study

7 May 2020 | By Victoria Rees (Drug Target Review)

Researchers have identified a structural loop in the SARS-CoV-2 S protein and a sequence of four amino acids that they say could help explain its high transmission rate.

news

Researchers analyse SARS-CoV-2 genome, identifying 198 mutations

7 May 2020 | By Victoria Rees (Drug Target Review)

After analysing the genomic diversity in SARS-CoV-2 by screening over 7,500 viruses from infected patients, researchers have offered clues for COVID-19 drug development.

news

Unique mutation in SARS-CoV-2 virus identified from next-generation sequencing

5 May 2020 | By Victoria Rees (Drug Target Review)

Next-generation sequencing has revealed an 81-base pair mutation of the SARS-CoV-2 virus, which could be used to develop new antivirals or vaccines.

article

Intravenous immunoglobulins, hyperimmunes and pandemic viruses

4 May 2020 | By Hannah Balfour (Drug Target Review)

David Johnson of GigaGen discusses how recombinant forms of intravenous immunoglobulins (IVIG) could overtake current IVIG therapies and be used in the treatment of COVID-19.

news

Researchers reveal structure of mega-enzymes from bacteria and fungi

1 May 2020 | By Victoria Rees (Drug Target Review)

Researchers have uncovered the structure of nonribosomal peptide synthetases (NRPSs), an important ingredient in drug production.

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Sequencing