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CRISPR identifies essential genes for cancer immunotherapy
Researchers have used CRISPR to stop the expression of individual genes in cancer cells, by knocking out every known protein-encoding gene in the human genome...
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CRISPR-Cas9 repairs genetic mutation in human embryos
"Well thought through and brilliantly executed" study shows different DNA-repair mechanism in embryos compared to iPSCs
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Over one thousand new microbial genomes discovered
Scientists at the U.S Department of Energy Joint Genome Institute (DOE JGI) have published a report that references 1,003 phylogenetically diverse bacterial and archaeal reference genomes.
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SOPHiA AI unlocks power of exome sequencing for clinical diagnostics
SOPHiA AI demystifies the secrets of the exome, home to 85% of disease-causing genetic variants. Clinicians can now get highly accurate results to diagnose patients for rare hereditary disorders.
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Using single-cell RNA sequencing to track stem cell development
Adult stem cells have the ability to transform into many types of cells, but tracing the path individual stem cells follow as they mature and identifying the molecules that trigger these fateful decisions are difficult in a living animal.
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WGS pinpoints DNA mutations to aid feline disorder treatment
Scientists at The University of Missouri-Columbia are using whole genome sequencing in order to identify genetic mutations that cause rare fatal diseases in cats.
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New meningitis bacteria research could hold key to developing improved vaccines
Meningococcal infections are the most common cause of bacterial meningitis in the United Kingdom, a life-threatening disease that poses a continuing threat worldwide. With growing fears around the increase of antibiotic-resistant bacteria, understanding why certain strains don't respond to vaccines could prove vital in helping reduce the number of global…
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Under the microscope with Labcyte
Dr Sheraz Gul, Head of Assay Development and Screening at the Fraunhofer Institute for Molecular Biology and Applied Ecology, answers questions on assay procedures...
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ProteinSimple Milo
12 January 2017 | By ProteinSimple
Single-Cell Western system capable of analysing protein expression in ~1,000 single-cells in parallel to unlock heterogeneity...
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Can genetic testing determine antimicrobial susceptibility?
Experts at EUCAST have found that genetic methods cannot yet be used to test for susceptibility in a number of important bacterial species.
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Valid biomarker signatures from liquid biopsies – how to standardise NGS
The advent of next-generation sequencing (NGS) techniques has revolutionised transcriptomics research and opened numerous avenues for scientific and clinical applications. While reverse transcriptase quantitative real-time polymerase chain reaction (RT-qPCR) is still considered the gold standard of gene expression analysis, its high throughput, single-nucleotide resolution and ever-plummeting costs have made NGS…
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Chemotherapy alternative: research shows Chinese medicine kills cancer cells
8 September 2016 | By Niamh Louise Marriott, Digital Content Producer
Compound kushen injection (CKI) has been used for years in Chinese clinics as an adjunct to western chemotherapy. Researchers used next generation...
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Bio-Rad CFX96 Touch™ Real-Time PCR Detection System
4 August 2016 | By Bio-Rad Laboratories
The CFX96™ Optical Reaction Module converts the C1000 Touch™ Thermal Cycler chassis into the powerful and precise CFX96 Touch Real-Time PCR Detection System...
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The impact of antibiotic exposure on the infant microbiome
15 June 2016 | By Victoria White, Digital Content Producer
An analysis of changes in the intestinal microbial population during the first three years of life has revealed some of the impacts of antibiotic exposure...
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Children with cancer to be offered gene testing in personalised treatment initiative
31 March 2016 | By Victoria White
Children with cancer will be offered testing for genetic mutations in their tumours as part of an initiative to personalise children’s cancer treatment...