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Stem-like T cells could improve immunotherapy treatments
Targeting stem-like T cells within certain lymph nodes could improve the number of cancer patients that respond to immunotherapy treatments.
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Stem Cells
Stem cells are undifferentiated biological cells that can differentiate into specialised cells and can divide to produce more stem cells.
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Innovative brain model provides patient-specific Alzheimer’s insights
Researchers have turned human stem cells into brain cells to create a new model that can predict cognitive decline rate on an individualised level.
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DNA mechanism discovery may open up Huntington’s disease therapies
Scientists unveiled how a DNA repair protein may prevent Huntington’s disease, presenting a new target in future therapies.
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Brain organoids mimic autism-related head size changes
Scientists have developed brain organoids that recapitulate the head size of autism patients to study the condition as well as possible therapies.
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On-demand webinar: An AI-based approach to phenotypic characterisation of neuronal cells
Evaluation of neurotoxicity effects is an active area of investigation in drug discovery and disease modeling.
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Cartilage growth gene TRPV4 shows promise for joint repair therapy
The discovery that the TRPV4 gene regulates cartilage growth could lead to treatments for osteoarthritis and other cartilage diseases.
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Drug Target Review update: exclusive report, online summit and more!
Hear about the latest Drug Target Review updates from Deputy Editor Victoria Rees who discusses our new report on AI & Informatics, the Cell & Gene Therapy Advancements online summit and much more!
whitepaper
Whitepaper: Accelerate antibody screening and characterisation
This whitepaper overviews use of Advanced Flow Cytometry to accelerate antibody screening and characterisation and reveal deeper biological insights.
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New skin cell mechanism discovery could treat muscle-related diseases
Scientists have identified the mechanism behind the conversion of skin cells into immature muscle cells, which could lead to therapies preventing muscle degeneration.
whitepaper
Whitepaper: Characterising astroglia models
This whitepaper describes several live-cell phenotypic analyses suitable for the characterisation of astroglia cells.
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“Noisy” gene expression may help improve stem cell therapies
Researchers have identified a process that amplifies changes in gene expression, which could be harnessed to accelerate stem cell differentiation.
whitepaper
Application note: High-content phenotypic profiling using the cell painting assay
The cell painting assay uses up to six fluorescent dyes to label and visualize a variety of subcellular structures at the single cell level.
news
Prime editing method corrects cystic fibrosis in stem cells
A team of scientists used a CRISPR-Cas9 technique known as prime editing to correct cystic fibrosis in cultured human stem cells.
whitepaper
Handbook: Latest edition live-cell analysis
The latest edition of the live-cell analysis handbook is a companion guide for live-cell analysis users. Includes discussion of live-cell analysis.
whitepaper
Whitepaper: Understanding T Cell phenotype and function
This whitepaper overviews the importance of understanding T Cell Biology to build better therapeutics, demonstrates use of advanced flow cytometry.