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Schizophrenia gene regulator identified by study
Using both computational models and stem cell-based experiments, researchers have identified a gene regulator of schizophrenia.
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Stem Cells
Stem cells are undifferentiated biological cells that can differentiate into specialised cells and can divide to produce more stem cells.
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Upstream Bioprocessing In-Depth Focus 2019
This In-Depth Focus features articles highlighting the importance of effective data management strategies as well as the recent trends in upstream bioprocessing.
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ALS pathological mediator identified by researchers
A potential target for ALS has been revealed by a study which found the Fos-B gene encouraged axonal branching.
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Pancreas-on-a-chip technology to aid in diabetes research
Scientists combine organ-on-a-chip and stem-cell technologies to make a powerful tool for diabetes research.
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What are the pros and cons of using organoids?
Dr Shona Lang investigates the advantages and disadvantages of using organoids within R&D, highlighting the most important questions to ask before using these models.
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Stem cell division in the geriatric brain blocked by signal
It has been discovered that Id4 controls whether stem cells enter cell division and may be relevant for treating neurodegenerative disease.
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Scientists develop retina-on-a-chip to study eye diseases
Combining organoid and organ-on-a-chip technologies, researchers have created a model which will allow them to study eye diseases and treatments for the retina.
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New drug target for glioblastoma identified by study
A new drug target for treating glioblastoma has been identified from a cellular pathway found to contribute to the spread of glioma stem cells.
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New study reveals causes of stem cell transplant rejection
A new study has shown that mutations in mitochondrial DNA induced by cell reprogramming may trigger an immune response.
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New CRISPR technique could alter the way we look at brain diseases
Researchers may have fundamentally altered the way scientists study brain diseases with new CRISPR technology.
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Nanotechnology platform could improve stem cell transplantation
A team has developed a technique for identifying pluripotent stem cells that could help research on transplantation medicine.
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Process for rejuvenating aged rat brain stem cells discovered
A research team has developed a method for regenerating old brain stem cells from rat models, which could be used to treat age-related brain diseases.
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Researchers grow genetically engineered mini livers to study disease
The first genetically modified mini human livers have been grown in a laboratory, to emulate liver disease progression and test therapeutics.
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Human stem cell combination could help damaged hearts live longer
A combination of heart cells derived from human stem cells could lead to developing a treatment for heart failure.
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Targeting a blood stem cell subset shows lasting gene editing
Scientists report how editing a portion of stem cells with CRISPR-Cas9 is sufficient for long-term reactivation of therapeutic haemoglobin.
