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Studying the effects of 3D genome organisation on gene silencing
Researchers explored the effects of loops and 3D genome organisation on gene silencing, and found that ‘cohesinopathies’ may be linked it.
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Stem Cells
Stem cells are undifferentiated biological cells that can differentiate into specialised cells and can divide to produce more stem cells.
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Case Study: Target discovery for rheumatoid arthritis
Learn more about Euretos computational disease model and how it predicts many of the known drug targets for RA.
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IPSCs used to study common genetic cause of chILD
Researchers observed many quantifiable differences between diseased cells made from affected children and their gene-edited cells.
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Developing in-vivo chimeric lungs with pluripotent stem cells
Reverse-blastocyst complementation elucidates the conditions required to form lungs in rat-mouse chimeric models.
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Neurodevelopmental defects seen in mini-brains with ANG mutation
Researchers found that ANG in its mutated form slows stem cell differentiation, resulting in neurodevelopmental defects in adult nerve cells.
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Article: Tips and Tricks for Leveraging Advanced Flow Cytometry
Tips and tricks for fully leveraging Advanced Flow Cytometry.
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The science of ageing and restoring healthspan
Contrary to popular belief, ageing is not caused by just random wear and tear of our bodies over time but is instead caused by a discrete set of biological mechanisms that we now better understand and can target with therapies. Life Biosciences are specifically focused on restoring and prolonging one’s…
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Unique self-activating proteins for drug discovery
Explore cutting-edge hit-to-lead insights through exclusive interviews and studies by leading experts in the field.
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Drug Target Review Proteomics eBook 2023
22 December 2023 | By
Download now! Drug Target Review breaks down the potential of stem cells for personalised regenerative medicine, offering practical insights into their role in healthcare.
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New insights about the development of hematopoietic stem cells
Understanding the involvement of Nod1 in the development of blood stem cells could greatly improve blood disorder treatments.
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Model for spinal muscular atrophy using human iPSCs
A 2D neuromuscular junction model enables high-throughput screening to discover new treatments for neuromuscular diseases.
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New gene found plays essential role in stem cell differentiation
Intestinal organoids allowed researchers to understand how Rnf43 and Daam1 influence the balance of stem cell renewal and differentiation.
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The IKAROS protein is crucial for B cell development
By mapping the genome, scientists have discovered how IKAROS enables differentiation of hematopoietic stem cells into B cells.
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New technology optimises mesenchymal stem cell extraction
A continuous sorting technique of stem cells on a DLD microfluidic platform may greatly advance cell therapy.
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Noncoding RNA could be a new target for acute myeloid leukaemia
Discovery about the DNA of leukaemia cells suggests promising target for gene therapy in paediatric oncology.
