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Infographic: Differentiating iPSCs – Which approach works best?
Download this infographic to find out why the method of generating human iPSC-derived cells matters.
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Stem Cells
Stem cells are undifferentiated biological cells that can differentiate into specialised cells and can divide to produce more stem cells.
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Drug Target Review Neuroscience ebook 2022
This ebook includes articles on the latest Alzheimer's research on how to potentially target tau and also how new human disease models can enable the development of transformational novel therapeutics.
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Scientists generate a mouse embryo model that develops neural tubes
The new mouse embryo model system promises to spur research into developmental health and disease.
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Optimising human small intestinal organoids by implementing Paneth cells
Researchers have succeeded in developing organoids that contain mature Paneth cells, which were not present in the previous human small intestinal organoids.
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Engineering cell lines for rare disease research and precision therapeutics
19 August 2022 | By Sartorius
Want to learn about the latest research and development of cell models in rare diseases? Then watch this virtual panel discussion to hear from industry experts.
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Using optogenetics to restore cell function
In a new study, researchers have found that light can be used to naturally balance a cell’s mitochondria.
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Application note: LlaMAbody™ camelid antibodies flyer
Single-domain antibodies (sdAb) are small, stable antibodies derived from camelids with a single monomeric variable domain.
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Potential target for type 1 diabetes treatment
Researchers have discovered a new pathway to the regeneration of insulin in pancreatic stem cells, findings that could move towards new therapies for type 1 and type 2 diabetes.
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Handbook: Western blot
Find western blot application protocols and troubleshooting tips for detecting proteins in this handbook.
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Video: Did you know that ddPCR technology offers lower variability for viral titer determination?
Droplet Digital PCR (ddPCR) offers greater accuracy and precision in quantifying viral titer in gene therapies.
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New immune targets to improve survival from sepsis
In a pre-clinical study, researchers from the US set out to develop a treatment for sepsis. Here, Daniel Morales-Mantilla, Dr Robin Parihar and Dr Katherine King, from Baylor College of Medicine, describe how they utilised haematopoietic stem and progenitor cell infusion to improve the survival of mice from sepsis.
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Using cortical spheroids to study endocannabinoids and autism spectrum disorder
The endocannabinoid system may play a role in the development of autism spectrum disorder and might be key to treating people with severe forms of the condition. In this commentary, Dr Karen Litwa, Assistant Professor at East Carolina University’s Brody School of Medicine, US explores how a bioelectronic assay is…
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Infographic: Detecting Mycoplasma contamination in your cell culture with confidence
This infographic will explore Mycoplasma contamination in cell cultures and the best technologies for detection.
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Product hub: A reproducible and scalable Huntington’s disease human cell model
Senior scientist Dr Tony Oosterveen discusses bit.bio’s new ioDisease Model portfolio, including new models for Huntington’s disease to help advance in vitro research and drug discovery.
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The promise of cell therapy: scaling up a new treatment paradigm for hearing loss
Expectations are growing worldwide for discoveries that will harness the potential of cell therapy, which has already brought breakthroughs in therapeutic areas where there is an unmet need, from oncology to ophthalmology and rare disease. In this article, Dr Terri Gaskell, Chief Technology Officer at Rinri Therapeutics, explores some of…