Interleukin-2 interactions revealed by researchers to aid in drug design
Using nuclear magnetic resonance spectroscopy, a study has shown that IL-2 can stimulate both effector T cells and regulatory T cells by adopting different structural forms.
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Using nuclear magnetic resonance spectroscopy, a study has shown that IL-2 can stimulate both effector T cells and regulatory T cells by adopting different structural forms.
A new 3D model of the surface of the coronavirus COVID-19 has been released, to aid researchers in the development of a treatment.
Scientists in Hong Kong have developed a novel optical technique that facilitates accurate tracking of hemogenic endothelium cells in zebrafish embryos, providing new insights into the mechanisms of blood formation and potential new understanding of diseases such as leukaemia.
A novel 4D printer has been created which can combine organic chemistry, surface science and nanolithography to design surfaces with organic or biological molecules for drug research.
Using fluorescent markers, researchers have developed Förster resonance energy transfer (FRET) to image the assembly, functions and interactions of molecules.
Researchers have used cryogenic electron microscopy to show that coronaviruses enter human cells through an interaction with angiotensin-converting enzyme 2 (ACE2).
Using cryogenic electron microscopy, a team has mapped the Spike protein on COVID-19, which could be used in the development of vaccines.
A new study has shown in three dimensions how drugs bind to HIV, which could be used to improve the design of drugs or develop novel therapies.
Research into drug targets for sleeping sickness parasite T. brucei has characterised the inosine-5'-monophosphate dehydrogenase (IMPDH) enzyme, providing a possible novel avenue for therapies.
Researchers have revealed the 3D structure of a membrane protein which plays a role in the development of conditions such as epilepsy and blindness.
Researchers have been able to image noroviruses, providing significant information for the development of therapeutics.
Researchers have identified a tiny hidden pocket on the NMDA receptor that could be targeted to treat strokes and seizures...
Liquid-phase electron microscopy could overcome limitations identified through traditional protein imaging techniques and through cro-electron microscopy...
Researchers have made discoveries about the formation of cellular components called membraneless organelles and the key role these organelles play in cells...
A cell structure identified has given an insight into how cells attach to their surroundings, and could be used to discover potential actions of new drugs...