news
Global consortium formed to combat unproven cell banking services
The International Society for Cell and Gene Therapy has created a group to tackle the rising number of commercial cell bank services that are misleading patients.
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T cells
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New drug shows promise as immune therapy for cancers
A therapy has been developed which uses a synthetic RNA molecule developed to fight viruses to trigger an immune response against tumours in mice.
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Study reveals potential of gamma delta T cells to combat breast cancer
Researchers have discovered that a specific subset of gamma delta T cells can be found in higher numbers of breast cancer survivor tissue, indicating its role in fighting the condition.
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Research reveals calcium signalling pathway in T cells
A study has uncovered the mechanism behind calcium entry and exit into T cells, which could be used in development of autoimmune disease treatments.
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Antibodies used to treat and reverse MS symptoms in mice
Researchers have identified a protein on the surface of cells that cause MS and have used antibodies as an effective treatment for the condition in mice.
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T cell homing beacons for lungs identified by researchers
Molecules that are critical for T cells to travel to and populate the lungs have been identified which could strengthen vaccines against influenza.
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Novel CAR T-cell therapy for leukaemia and lymphoma
Scientists in the US have developed a promising new CAR T-cell therapy that targets the BAFF-R protein, which has demonstrated superior cancer destruction to existing FDA-approved CAR-T therapies.
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Transplanted brain stem cells survive without anti-rejection drugs in mice
An experiment with mice has successively blocked the immune system's T cells from killing transplanted cells.
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Study finds B cells could improve immunotherapies for cancer
Researchers have discovered that B cells aid T cells in fighting cancer, which could be an area of development for immunotherapies.
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CAR T-cell therapy could be harnessed to treat heart disease
New study finds immunotherapy reduces cardiac fibrosis and restores heart function in mice after cardiac injury.
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T-cell subset association with type 1 diabetes demonstrated by study
A new study from the University of Eastern Finland has shown that peripheral T helper cells may have a role in the development of type 1 diabetes.
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Anti-viral immune discovery could lead to improved vaccines
A molecular switch that impacts immune responses to viral infections has been identified which could lead to better strategies to develop vaccines.
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Industry objects to unproven T-cell preservation services
The ISCT is objecting linking the benefits of cellular immunotherapy with third party offerings of T-cell banking for future therapeutics.
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OX40-expressing follicular helper T cells can control rheumatoid arthritis
New study shows that a subset of follicular helper T cells contributes to the hyposialylation of autoantibodies in rheumatoid arthritis.
whitepaper
Whitepaper: CD4+ T-Cell Subsets
CD4+ T-cells play a central role in directing adaptive immune responses against invading microbial pathogens.