news
Extracellular vesicles could be personalised drug delivery vehicles
Researchers developed an approach and platform to create large amounts of fillable and targeted nanovesicles to deliver drugs to tumours in mice...
List view / Grid view
T cells
news
Preventing exhaustion in immune cells boosts immunotherapy in mice
Research shows that preventing or reversing ‘T-cell exhaustion’ with targeted therapies could enhance the effects of immunotherapy.
news
Study suggests PD-1 inhibitors against aggressive pediatric brain cancer subtype
A study has laid the groundwork for the use of PD-1 inhibitors with an aggressive form of brain cancer, namely supratentorial pediatric ependymoma.
news
Gimap5 gene mutations found to trigger immune diseases
Scientists discovered how a gene mutation affects T cell function to promote immune disorders...
news
Genomic tools reveal diverse behaviour in immune cells
New research from La Jolla Institute for Allergy and Immunology using single-cell transcriptome analysis yields greater understanding of the human immune system.
news
APC-mimetic scaffolds could facilitate more effective precision immunotherapies
Amplifying patient-specific T cells outside the body could increase the efficiency of cancer immunotherapies...
news
Immune cells dictate tumour progression
Analysing individuals' genotypes and immunotypes could yield customised treatments for prostate cancer...
news
Researchers use AI technology to chart immune cell receptor
Johns Hopkins scientists have used a form of artificial intelligence to create a map that compares types of cellular receptors, the chemical ‘antennas’ on the surface of immune system T-cells.
whitepaper
Application note: Screening for inhibitors of PD-1 and PD-L1 binding with AlphaLISA technology
In this application note, PerkinElmer demonstrate the utility of an AlphaLISA assay for screening biotherapeutic antibodies and compounds that block binding of human PD-1 and PD-L1.
news
Lung tumours communicate with bones to progress disease
Scientists at Massachusetts General Hospital (MGH) have identified how a type of lung cancer co-opts a portion of the immune system via bone marrow to increase tumour progression.
news
Synthetic T-cells engineered to combat cancer
Researchers have engineered T-cells in the laboratory to combat tumours...
news
DNA-based Zika vaccine found effective at inducing immune response
A new generation DNA-based Zika vaccine is the first to demonstrate both safety and the ability to elicit an immune response against Zika in humans...
news
Nanoparticles give disease-fighting properties to cells
A new biomedical tool has been developed using nanoparticles that deliver transient gene changes to targeted cells...
news
Researchers find switch that turns on immune cells tumour-killing ability
Researcher have shown how a mRNA molecule known as Lethal-7 serves as a molecular control hub to direct the function of cytotoxic T lymphocytes...
news
Tumours detected with sugar molecules
Scientists have synthesised a complex sugar structure that specifically binds to the tumour protein Galectin-1...