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T cells

news

Replication proteins a potential new target for COVID-19 vaccines

12 November 2021 | By Anna Begley (Drug Target Review)

A new study claims that future COVID-19 vaccines should activate T cells to attack infected cells expressing replication proteins.

podcasts

Episode 3 – Cell & gene therapy with Dr Sam Wadsworth, Ultragenyx Pharmaceutical & Dr Eric Ostertag, Poseida Therapeutics

1 November 2021 | By Drug Target Review

Tune in to this podcast to learn about AAV vectors for gene therapy delivery and engineering CAR T cells against solid tumours.

video

Engineering better CAR T cells with Professor Ann Ager, Cardiff University

27 October 2021 | By Drug Target Review

Watch this exclusive interview with Professor Ann Ager, Cardiff University, to discover how CAR T cells could be targeted against solid tumours.

news

Novel strategy successfully suppresses HIV infection in mice

25 October 2021 | By Anna Begley (Drug Target Review)

A new method, called synapse for T-cell activation (synTac), can attack HIV-infected T cells and may be a new cure for HIV and other diseases.

article

High-throughput 3D cell migration assays in organ-on-a-chip technologies

30 September 2021 | By Désirée Goubert (MIMETAS), Dr Lenie van den Broek (MIMETAS), Luuk de Haan (MIMETAS), Thomas Olivier (MIMETAS)

Organ-on-a-chip models can provide an alternative to cell cultures, animal models and traditional assays. In this article, Dr Désirée Goubert, Thomas Olivier, Luuk de Haan and Dr Lenie van den Broek explore the advantages of organ-on-a-chip technologies and how they can enable the in vitro study of three-dimensional (3D) cell migration in…

Yellow antidepressant pills with smiley faces drawn on

news

Antidepressants inhibit growth of pancreatic and colon cancers in mice

29 September 2021 | By Anna Begley (Drug Target Review)

Scientists have discovered that approved antidepressant drugs cause immune cells to recognise and eliminate tumour cells in mouse models.

news

New AI method could aid in development of T cell-based cancer therapies

24 September 2021 | By Anna Begley (Drug Target Review)

An artificial intelligence technique can identify which neoantigens are recognised by the immune system, possibly improving cancer prognosis and treatment.

news

Lymph node-targeted vaccine elicits COVID-19 protection in vivo

23 September 2021 | By Anna Begley (Drug Target Review)

Elicio Therapeutics’ lymph node-targeting vaccine displayed cellular and humoral immunity to SARS-CoV-2 in a pre-clinical study.

news

Novel tool can estimate number of T cells in cancer tumours

10 September 2021 | By Anna Begley (Drug Target Review)

Researchers have developed a new method that can rapidly count the number of T cells in a tumour, helping to predict patient response to therapies.

news

Stem-like T cells could improve immunotherapy treatments

7 September 2021 | By Anna Begley (Drug Target Review)

Targeting stem-like T cells within certain lymph nodes could improve the number of cancer patients that respond to immunotherapy treatments.

news

RN7SL1 RNA shown to activate T cells to fight against cancer

6 September 2021 | By Anna Begley (Drug Target Review)

A new study found that the RNA RN7SL1 can activate T cells to seek out cancer cells, potentially improving cellular treatments.

news

Immune cell changes detected in Waldenstrom macroglobulinemia (WM)

2 September 2021 | By Anna Begley (Drug Target Review)

A new study has found mutations originating in blood progenitor cells, possibly leading to Waldenstrom macroglobulinemia (WM) therapies.

news

Scientists develop novel strategy for tuberculosis vaccine

25 August 2021 | By Anna Begley (Drug Target Review)

A research team have created a new strategy for developing an effective vaccine against a widespread form of tuberculosis.

White blood cells as part of immune response to leukaemia

news

Existing drug may improve immune response to leukaemia treatment

18 August 2021 | By Anna Begley (Drug Target Review)

Researchers identified the inhibitor JQ1 as a potential drug to improve immune response to CAR T-cell therapies in leukaemia patients.

news

Researchers reveal potential cause of COVID-19 aftereffect in children

13 August 2021 | By Anna Begley (Drug Target Review)

Scientists have uncovered an important clue to the COVID-19-related multisystem inflammatory syndrome in children (MIS-C).

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T cells