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Target Validation

ProteinSimple Milo

12 January 2017 | By ProteinSimple

Single-Cell Western system capable of analysing protein expression in ~1,000 single-cells in parallel to unlock heterogeneity...

New Strategy to Identify Small Molecule Therapies

webinar

New strategy to identify small molecule therapies

1 December 2016 | By Charles River

This webinar details a successful new strategy to identify small molecule therapies to treat protein-destabilizing monogenic disorders...

article

Browsing for drug targets

8 March 2016 | By Edward D. Zanders, PharmaGuide Ltd, Cambridge, UK

Here, Edward D. Zanders explains his motivation behind writing ‘Human Drug Targets a Compendium for Pharmaceutical Discovery’ - a collection of current and potential drug targets mapped to human genes curated by the HGNC...

news

Biogen joins the Centre for Therapeutic Target Validation

8 February 2016 | By Victoria White

Biogen’s new membership follows the launch of the new CTTV Target Validation Platform, which helps researchers identify therapeutic targets for new medicines...

Genomic support for target selection and validation in drug development

webinar

Genomic support for target selection and validation in drug development: design of a new genotyping array

22 November 2015 | By Illumina

In this webinar, we focus on the use of microarray technology in drug development...

news

GPR3 identified as a new target for Alzheimer’s disease treatment

15 October 2015 | By Victoria White

Researchers have determined that the protein GPR3 might play an important role in alleviating the cognitive deficits of 'amyloid plaques'...

news

Biogen to work with Genomics to refine drug target selection

5 October 2015 | By Victoria White

Biogen will leverage findings from Genomics’ integrated database and analysis tools, which will be used to guide drug research and development...

news

New method of investigating human lung tissue enables improved drug target validation for COPD treatment

30 April 2015 | By Victoria White

Scientists at Helmholtz Zentrum München have succeeded in testing the effectiveness of new approaches for treating COPD on ex vivo 3D-LTCs...

article

Molecular Target Validation in preclinical drug discovery

2 May 2014 | By Isabella Gashaw (Bayer HealthCare Pharmaceuticals), Karl Ziegelbauer (Bayer HealthCare Pharmaceuticals), Khusru Asadullah (Bayer HealthCare Pharmaceuticals), Martin Bechem (Bayer HealthCare Pharmaceuticals)

Preclinical drug target validation has the aim to increase confidence in a particular drug target. The process proves the initial hypothesis that a particular molecular target is key or even causative for pathogenic or symptomatic mechanisms in a disease. Several success factors seem to be of particular importance for the…

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Target Validation