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Novel modalities of recently approved drugs
Dr Sheraz Gul reviews the drug approvals from 2021 and highlights the novel modalities of molecules that target KRAS and HIF-2α, which have historically been considered as undruggable.
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Targets
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Scientists identify protein which may lead to mesothelioma treatment
A new study in zebrafish has shown the Hand2 protein may play a role in the origin of mesothelioma, presenting a target.
news
Nanotherapy could protect premature babies
Pre-clinical research in newborn rats found that a nanotherapy could prevent chronic lung disease in premature babies.
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New findings may lead to cardiovascular disease treatment
New research has found that immune cells produce a chemical messenger that prevents heart disease–related inflammation
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Drug Target Review Assays ebook 2022
In this ebook, you can find articles on the development of novel assays and technology - download now for free!
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An equal seat at the table for AI in pharmaceutical discovery
This article explores the current state of artificial intelligence (AI) in drug discovery and development, discussing the obstacles holding back wider adoption. Dr Mark Eller, Senior Vice President of Research and Development at Aria Pharmaceuticals, makes the case that to succeed, AI must be integrated as a partner alongside core…
news
New screening method reveals why Alzheimer’s drugs often fail
Researchers have developed a new method to screen drugs for Alzheimer’s disease, shedding light on why current drugs have failed and identifying novel drug targets.
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Research reveals CDH17 represents a new approach to treat solid cancers
Pre-clinical research has found that CAR T cells can suppress gastrointestinal cancer cells without causing harm to healthy tissues.
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NanoTemper Technologies launches Spectral Shift, a breakthrough technology that changes the game for affinity-based screenings
NanoTemper Technologies has announced the launch of Spectral Shift technology with its Dianthus instrument.
webinar
timsTOF MALDI PharmaPulse, a trapped ion mobility-enabled mass spec solution for label-free HTS in drug discovery
25 March 2022 | By Bruker Daltonics
Watch our free on-demand webinar to discover how the new timsTOF MPP product solution, with its dedicated MALDI PharmaPulse 2023 HTS software suite, improves data quality and accelerates high-throughput screening in drug discovery.
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The case for improving absorption for cannabinoids using ethosomes
Michael Sassano and Anthony DeMeo from Somai Pharmaceuticals discuss using ethosomes as an improved method to deliver cannabinoids to the human body.
news
Defective mitochondria could be repaired using gene-editing techniques, study finds
Researchers have shown that it could be possible to modify the mitochondrial genome, paving the way for new treatments for incurable mitochondrial diseases.
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New study highlights the possibility to target gene editing in the lungs
Researchers have been able to significantly reduce tumours in a pre-clinical model of a rare genetic lung disease.
whitepaper
Whitepaper: In-depth look into anti-idiotype antibodies
In this article, Sino Biological will highlight the applications of anti-IDs, and conclude with our two featured case studies on anti-ID development.
whitepaper
Article: Bispecific antibodies: Rising stars in antibody therapeutics
In this article, Sino Biological will highlight the design and engineering of bispecific antibodies, and bsAbs expression and production.