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Article: Bispecific antibodies: Rising stars in antibody therapeutics
In this article, Sino Biological will highlight the design and engineering of bispecific antibodies, and bsAbs expression and production.
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Scientists discover new features of rare lung disease
Researchers at the US National Heart, Lung, and Blood Institute have discovered new insights about lymphangioleiomyomatosis, a rare lung disease that affects about one in 200,000 Americans.
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Engineered airway lining created to study how COVID-19 affects respiratory tracts
Researchers have made a respiratory model of COVID-19, made from patient-derived stem cells, to understand how the virus affects respiration and which could be used to test possible drugs.
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Study identifies new therapeutic target for haematologic malignancies
Using chemical genetic screening and pre-clinical model studies, researchers have discovered that inducing ubiquitin-mediated degradation of mutant EZH2 could provide a more effective treatment strategy for haematologic malignancies.
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New research sheds light on what influences target protein binding time
The length of time that drug molecules attach to their target protein varies greatly and impacts the protein’s behaviour and drug efficacy. In a new study, scientists in Finland have identified some causal factors for this variance, with the hope it will bring clarity for drug developers.
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New model yields promising gene therapy for heart condition
Scientists in Japan have developed a credible heart cell model for arrhythmogenic cardiomyopathy and observed a positive response in the condition using PKP2 gene therapy.
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Whitepaper: How to successfully use iPSCs for disease modelling
Benefits and key considerations of using human iPSC-derived disease models in drug discovery.
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Opportune identification of novel multiple myeloma target
During investigations into the tropical disease Buruli ulcer, researchers have instead identified a promising new avenue for potential treatments for multiple myeloma.
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Ingenious AI method for improved target identification
A research team based at Skoltech in Russia has developed an artificial intelligence-driven solution for highly accurate detection of efficacious binding sites to expedite drug discovery.
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Brochure: Automation drug discovery
Accelerate your drug discovery workflows efficiently and cost-effectively with lab automation solutions from Beckman Coulter Life Sciences.
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Product hub: Introducing the latest addition to Thermo Fisher Scientific’s genome editing portfolio – InvitrogenTM TrueCutTM HiFi Cas9 Protein!
Read about the latest addition Invitrogen™ TrueCut™ HiFi Cas9 Protein to support your application and research goals.
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Researchers investigate gene network to identify “cancer driver genes”
The new study looked at the network of gene-gene interactions associated with cancer onset and progression to identify therapeutic targets.
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Novel screening method identifies lead molecule for GPCR dimerisation
The new high-throughput screening method identified nine lead molecules for rhodopsin dimerisation that may lead to next-generation medicines.
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Prostate cancer organoids pave way towards precision oncology
Scientists develop organoid models of neuroendocrine prostate cancer to study EZH2 inhibitors and reveal a potential new target.
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Genetic study could influence the development of COVID-19 therapies
The study is the first in-depth look at links between COVID-19 severity and gene expression in immune cells and may guide future therapies.