Technology

High-res 3D structure of proteins inside living eukaryotic cells determined

3 June 2019 | By Drug Target Review

Nuclear magnetic resonance measurement and state-of-the-art computational science reveal protein structures in higher eukaryotic cells.

UK drug discovery market ‘thriving’ says new report

27 May 2019 | By Drug Target Review

A new report reveals a thriving service and supply sector for the UK in addition to its research and development biotechs.

Gene editing tools market valued at $258 million in 2018

23 May 2019 | By Drug Target Review

The global gene editing tools market is estimated to have accounted for more than US$258 million in terms of value in 2018.

AI-driven automated chemistry as a tool to accelerate drug discovery

15 May 2019 | By Alexey Zakharov (National Center for Advancing Translational Sciences)

Typically, early drug discovery campaigns start with the screening of chemical libraries to identify candidate chemotypes modulating a particular target and/or phenotype. Success of the primary screening depends on multiple factors related to both biology and chemistry. These include the target’s druggability, sensitivity and specificity of assay system, composition and…

Innovative mechanobiology research expands understanding of cells

13 May 2019 | By Drug Target Review

Researchers have developed a new technology that allows them to probe cell changes without disturbing the cell’s physiology.

Magnetic microbots could help drug-delivery nanoparticles reach their targets

3 May 2019 | By Drug Target Review

MIT engineers have designed tiny robots that can help drug-delivery nanoparticles push their way out of the bloodstream and into a tumour or another disease site.

New information on the pathological mechanisms of Alzheimer’s disease

21 November 2018 | By Drug Target Review

Researchers have indicated that the accumulation of pathological tau triggers a safety valve mechanism in the otherwise well-regulated cell membranes...

Charles River and Distributed Bio enter exclusive partnership to create an integrated antibody discovery and development platform

5 November 2018 | By Charles River Laboratories

Charles River Laboratories International, Inc. announced that it has entered into an exclusive partnership with Distributed Bio, Inc., a leader in the computational design and optimisation of antibody discovery platforms...

Synthetic biology in drug discovery

13 September 2018 | By Dr Tim Brears - Chief Executive Officer - Evonetix

Synthetic biology is broadly defined as the design and construction of novel artificial biological pathways, organisms or devices; or the redesign of existing natural biological systems.1 It brings together a range of disciplines and skills, from biology and chemistry to computing, bioinformatics and engineering.

The European Antibody Congress is returning to the city of Basel

4 September 2018 | By The European Antibody Congress

The European Antibody Congress is returning to the city of Basel for its 14th year on the 29-31 October 2018, and here is everything you need to know about our biggest event yet...

Novel PET imaging could guide therapy for type 1 diabetes

6 August 2018 | By Drug Target Review

Since beta cells and neurological tissues have common receptors, researchers screened brain radioligands for their ability to identify beta cells...

Applications of molecular imaging in drug development

25 July 2018 | By Ben Burke (University of Hull and Castle Hill Hospital), Steve Archibald (University of Hull and Castle Hill Hospital)

The world of healthcare is rapidly evolving. With an ageing population, comes a significant increase in cancers, metabolic diseases and neurodegenerative disorders. New drug candidates are required; however drug development remains a lengthy and expensive process, with the average timeline now over 10 years and costs continuing to rise...

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ELRIG UK hosts inaugural Discovery Technologies event

8 May 2018 | By ELRIG

ELRIG (European Laboratory Research & Innovation Group) has announced its first Discovery Technologies meeting, which will take place at Alderley Park, located near Macclesfield in Cheshire.

SMi’s 5th Annual Molecular Diagnostics Conference 2018 agenda released

24 April 2018 | By SMi Group

SMi proudly presents its 5th annual conference on Molecular Diagnostics, taking place at the Holiday Inn Kensington Forum, London, UK on 9 and 10 July 2018, with a half-day post-conference workshops on 11 July 2018...