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New target in the fight against heart disease
US scientists have new insight into how heart cells enable unhealthy growth, and identify a new target to intervene against heart disease.
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Therapeutics
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Immune cells in ALS patients: predicting disease progression
Swedish researchers have discovered that by measuring immune cells in the cerebrospinal fluid when diagnosing ALS, it is possible to predict how fast the disease may progress.
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What parts of a tumour are linked to muscle wasting?
US researchers found that the severity of muscle wasting from cancer is related to the type, size and location of the tumour, in mice.
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Deteriorating neurons: the source of human brain inflammation in Alzheimer’s disease
US researchers administered a therapy to Alzheimer’s patient-derived neurons in the lab, eliminating deteriorating cells, leading to positive consequences for the remaining healthy cells.
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Cardiac regeneration: a new electrical therapy for CVD
US researcher from the University of Houston is the first to report a novel cell therapy process for heart regeneration, that conducts electricity throughout the heart to enable rhythmic heartbeat and repair diseased hearts.
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Researchers find breast cancer protein that could predict chemotherapy sensitivity
Researchers have identified a protein that, when present in high amounts in breast cancer tumours, is an indicator of whether DNA-damaging therapies will work or not.
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New drug shows promise for fighting both COVID-19 and cancer
US researchers showed that the protein: GRP78, implicated in COVID-19 and cancers, is effected by the new drug HA15.
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Cancer immunotherapy adapted to treat COVID-19 variants
US researchers have utilised a cancer immunotherapy technique, CAR-T cell method to effectively eliminate SARS-CoV-2 virus pre- and post-infection in vitro.
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Novel protein identified that contributes to tau neurotoxicity in Alzheimer’s disease
US researchers have identified a protein that interacts and enhances the spread of neurotoxic species of tau, which is primarily found in neurons that appear abnormal in the brains of Alzheimer’s disease patients.
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Five recent CRISPR drug target discoveries
This article highlights five of the latest findings revealed using CRISPR that could be used in the development or design of new therapies.
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Probiotic ‘backpacks’ show promise for treating IBD
US researchers have uncovered the uncapped potential that gut-friendly bacteria has for improving treatments of inflammatory bowel disease (IBD).
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A new weapon against antibiotic-resistant bacteria
A UNIGE team reveals that a drug used against herpes can fight a bacterium that is resistant to most antibiotics by weakening its defence mechanisms.
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Potential treatment for neurological disorders targets brain cells
UCL researchers have developed a possible new treatment for neurological and psychiatric diseases, that works by reducing the excitability of overactive brain cells.
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Protein inhibitor could be new treatment for liver cancer
US scientists have found strong evidence for testing VCU-manufactured drugs in liver cancer.
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Metastatic potential of cancer cells increased in high viscosity environments
UPF and John Hopkins scientists have discovered how cancer cells exposed to high viscosity environments change their movements to improve their invasiveness and favour metastases.