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Product hub: Targeted protein degradation – next-generation therapeutics
Helen Harrison, Director of Screening at Amphista Therapeutics, discusses targeted protein degradation (TPD) and the discovery of drugs in this area.
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Therapeutics
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Product hub: Uncover spatial biology secrets. Gain disease insights.
Discover why the Hyperion+ Imaging System is the standard to assess tumour-immune interactions and get deep single-cell insights.
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Product hub: CD34+ haematopoietic stem cells: One cell type, multiple viable sources
Learn how you can mobilise CD34+ haematopoietic stem cells and how they can be isolated immediately after collection.
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Product hub: Light the path to your next neuroscience discovery with a new ultrasensitive NF-L immunoassay
Discover all the ways you can harness ultrasensitive immunoassays to stay at the forefront of neuroscience research.
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Building a powerful portfolio of sepsis biomarker signatures for therapeutic clinical trials
In this Q&A, Immunexpress Chief Executive Officer Dr Rolland Carlson and Chief Scientific Officer Dr Richard Brandon discuss key aspects for molecular diagnostic discovery and development platforms, including how to best leverage microarray and next-generation sequencing (NGS) tools.
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Synthetic biology is ready for the therapeutic limelight
After initially serving as a proving ground for integrating forward engineering principles into living cells, synthetic biology is making waves across diverse therapeutic areas. In this article, Dr Dan Mandell, Co-Founder and CEO of GRO Biosciences, explains how the field is reshaping our understanding of the limits of cell- and molecular-based medicines.
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A new strategy to overcome tumour-induced immunosuppression
Researchers have found that blocking key enzymes could boost anti-cancer T cell responses and resistance to immunosuppression.
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Study reveals novel insights into Crohn’s disease
The findings by Massachusetts General Hospital could point to a potential target to treat Crohn’s disease.
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Gene Lx9c11 helps mice survive virus infections
Researchers have discovered that “jumping gene” Lx9c11 has a profound effect on the immune system to virus infection.
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Sound and electrical body stimulation could treat chronic pain
12 August 2022 | By
A new technique could relieve pain for individuals with various chronic and neurological conditions.
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Novel insights into the genetic and molecular machinery that causes Alzheimer’s disease
Researchers have gained a clearer understanding of the genetic and molecular machinery in human microglia, findings that may provide insight into Alzheimer’s diseases development.
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A new study has highlighted how an antibody strengthens bonds between cells
The monoclonal antibody 19A11 binds E-cadherin, a protein that helps cells stick together, especially in epithelial layers that line the skin, the gut and other organs.
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An EGFRvIII-targeted immune-based therapy could potentially treat glioblastoma
A T-cell bispecific antibody shows potent anti-tumour activity in preclinical models of epidermal growth factor receptor variant III (EGFRvIII) mutant glioblastoma.
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Scientists create a nanobody that could treat Parkinson’s disease
Researchers have developed a nanobody that can penetrate the tough exterior of brain cells and untangle misshapen proteins that lead to Parkinson’s disease.
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Progress towards a stem cell-based therapy for blindness
Scientists are developing an effective stem cell-based therapy to regenerate photoreceptors cells and restore sight in people with blindness.