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Cannabidiol analogue could enhance chemotherapy by preventing neuropathic pain
A new study has revealed a cannabidiol analogue can possibly prevent neuropathic pain induced by chemotherapy, as well as being beneficial against cancer.
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Therapeutics
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Study highlights possibility of using 3D organoids of the cervix to test drugs
A new study modelled chlamydia and HPV co-infection in patient-derived ectocervix organoids to reveal distinct cellular reprogramming.
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Scientists discover new features of rare lung disease
Researchers at the US National Heart, Lung, and Blood Institute have discovered new insights about lymphangioleiomyomatosis, a rare lung disease that affects about one in 200,000 Americans.
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Possible improvement to Parkinson’s disease treatment shown in study
Research from the University of Copenhagen reveals how Deep Brain Stimulation treatment of walking problems in Parkinson’s disease could be optimised by targeting specific neurons in the brainstem.
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New pre-clinical study demonstrates innovative approach to treating brain diseases
Researchers have been able to slow down the progression of glioblastoma in mice, the most common adult brain cancer.
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Game-changing model to identify drugs that may slow AMD
Researchers have identified potential age-related macular degeneration drugs using a novel stem-cell based research tool.
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Possible connection between HIV and tuberculosis revealed
A recent study has shown that antiretroviral therapy timing impacts the animal version of HIV and latent tuberculosis.
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Bone marrow stem cell transfusions show promise as potential treatment for sepsis
New research has shown that one-time infusion of stem cells from bone marrow improves the survival of mice with sepsis.
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Possible new class of compounds to treat diabetes identified
A recent pre-clinical study from Washington University School of Medicine showed that a new class of compounds can potentially improve multiple aspects of metabolic syndrome, including diabetes.
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Engineered airway lining created to study how COVID-19 affects respiratory tracts
Researchers have made a respiratory model of COVID-19, made from patient-derived stem cells, to understand how the virus affects respiration and which could be used to test possible drugs.
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Novel antibody could reduce SARS-CoV-2 transmission
Researchers at UC Davis Health have engineered an antibody that interferes with a critical cell mechanism to reduce transmission of the virus that causes COVID-19 in lab tests.
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Promising target for osteoporosis treatments found in new study
By identifying a mechanism behind bone strengthening in response to stress, researchers have found a possible new target for treating conditions that weaken bones.
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Study identifies new therapeutic target for haematologic malignancies
Using chemical genetic screening and pre-clinical model studies, researchers have discovered that inducing ubiquitin-mediated degradation of mutant EZH2 could provide a more effective treatment strategy for haematologic malignancies.
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Novel method for chemo capture – up to three times more effective
A team of researchers in the US has devised a new means of removing excess chemotherapy drugs from a patient’s bloodstream, with potential for wider clinical and materials science applications.
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Scientists discover compound to combat multidrug-resistant bacteria
Taking a novel approach to antibiotic discovery, researchers at Rockefeller University have hit upon a promising solution to the problem of superbugs – a pervasive threat in hospitals the world over.