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NPSR1 gene discovered as a key cause of endometriosis
NPSR1 has been identified as a genetic cause of endometriosis, revealing a potential drug target that may lead to better therapies.
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Brain organoids mimic autism-related head size changes
Scientists have developed brain organoids that recapitulate the head size of autism patients to study the condition as well as possible therapies.
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Cartilage growth gene TRPV4 shows promise for joint repair therapy
The discovery that the TRPV4 gene regulates cartilage growth could lead to treatments for osteoarthritis and other cartilage diseases.
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Lung fibrosis in mice successfully reversed by scientists
A team of researchers have reversed lung fibrosis in a mouse model, highlighting a new therapeutic target for pulmonary fibrosis.
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New study may improve enzyme replacement therapy for Pompe patients
Researchers have developed a new method that could make enzyme replacement therapy more efficient for Pompe disease treatment.
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High-intensity focused ultrasound therapy moves closer to the clinic
Researchers are investigating how high-intensity focused ultrasound (HIFU) can work on a cellular level to treat a range of cancers.
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AI method reveals 17 existing drugs that may fight against COVID-19
Scientists used artificial intelligence to identify 17 existing drugs that could kill SARS-CoV-2 in cells, including a dietary supplement.
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Scientists discover new clue for platelet activation to target thrombosis
Researchers have revealed a novel mechanism for platelet activation, suggesting a potential target for antithrombotic therapy.
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Genome-editing strategy may become novel Alzheimer’s treatment
Scientists have developed a new strategy using brain-wide genome-editing technology that reduced Alzheimer’s disease pathologies in mice.
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Existing drug may improve immune response to leukaemia treatment
Researchers identified the inhibitor JQ1 as a potential drug to improve immune response to CAR T-cell therapies in leukaemia patients.
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Enzyme discovery could fight against cancer and viral infections
A new study has identified a vital enzyme, known as APOBEC3A, that could lead to new treatments against cancers and viral infections.
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Targeting interferon kappa could control psoriasis inflammation
Scientists found that changing interferon kappa levels altered the severity of psoriasis inflammation and cytokine production in mice.
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TREM2 regulation to prevent neurodegeneration is possible, study shows
Scientists used a synthetic thyroid hormone in mice to regulate the TREM2 gene implicated in diseases such as Alzheimer’s and Parkinson’s.
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Inhibiting REST gene could be clue to new diabetes treatments
A study has shown that inhibiting the REST gene boosted insulin-producing cells during early pancreas development in animals.
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Uncovering ketamine’s mechanisms helps identify depression treatment
A new study has revealed how ketamine exerts its antidepressant effect, raising hopes of finding new treatment options for the disease.
