news
Platelet-based therapeutic formulation targets tumours in mouse models
A new delivery vector using platelets has shown success in pre-clinical trials at delivering photothermal particles and immunostimulators to tumours.
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Therapeutics
news
Inhibiting IRE1α pathway could be novel therapeutic strategy for lupus
A study has revealed that blocking a molecule called IRE1α could prevent the release of neutrophil extracellular traps in lupus pathogenesis.
news
Aptamer inhibits SARS-CoV-2 with novel mechanism of action, study shows
An aptamer that can bind a different part of SARS-CoV-2 than known inhibitors could enhance treatments against coronavirus mutations.
podcasts
Episode 1 – Dr Sri Gopal, Janssen Pharmaceuticals
Listen along to learn more about drug development for schizophrenia from Dr Sri Gopal, Head of Psychiatry R&D for Janssen!
article
Drug Target Review – Issue 1 2021
In this issue, find articles discussing how high-throughput experimentation can enhance automated molecular discovery, why bNAbs present a promising COVID-19 treatment and how a novel rhinovirus vaccine was developed. Also included are features on immuno-oncology, cell line development and assays.
news
High-CBD cannabis extracts could provide COVID-19 treatment
Cannabidiol's (CBD) anti-inflammatory properties could be harnessed to treat or prevent COVID-19, according to a new study.
news
New inhibitor found to combat drug-resistant cancer cells
A team has developed a novel inhibitor that blocks a protein in cancer cells, making drug-resistant tumours respond to chemotherapy.
article
Developing bioenergetic nanocatalysts, a novel approach to treat neurodegeneration
Mark Mortenson, CSO of Clene Nanomedicine, discusses the use of proprietary gold nanocrystals as catalysts to prevent the progression of, and act as a treatment for, neurodegenerative disease.
news
New drug shows potential as prophylactic for Alzheimer’s disease
In pre-clinical studies, a novel treatment decreased plaque formation, meaning it could be used to prevent Alzheimer's disease.
news
Screening by compound activity could accelerate drug discovery
Researchers have developed a new screening technique called biological activity-based modelling to identify drug candidates.
webinar
The discovery and challenges of antibodies targeting GPCRs
26 February 2021 | By Domain Therapeutics
Watch our on-demand webinar which focused on the progress achieved in G protein-coupled receptor (GPCR) therapeutic antibody-based discovery and development.
news
Drugs with potential to stop plaque build-up in arteries identified
A new compound can inhibit the build-up of plaque in arteries and prevent atherosclerosis, researchers have shown.
news
UK Government to fund four studies investigating long COVID
The UK Government will give £18.5 million in funding to four studies researching the causes and potential treatments of long COVID.
news
Team modifies therapeutic molecule to improve stroke treatment
Researchers have shown that adding a polymer to glutamate-oxaloacetate transaminase means the molecule can treat stroke for up to six days in rats.
news
LEAP proton therapy could target cancer cells that resist treatment
A proton therapy that targets cancer cells which are resistant to treatment has shown success, sparing surrounding healthy cells.
