news Ru-Pt conjugate drug could be the future for cancer therapies 16 March 2020 | By Hannah Balfour (Drug Target Review) Researchers combined cisplatin, an enhancer and a photodynamic therapy (PDT) drug into a single conjugate that had 10 times the efficacy in treating treatment resistant cancer cells.
article Safer and more affordable medicine for all? How pharmacogenomics may level the playing field 16 March 2020 | By Drug Target Review Dr Mike Tocci discusses how pharmacogenomics can revolutionise medical research and improve the efficacy and quality of drugs.
news 3D visualisation of COVID-19 surface released for researchers 13 March 2020 | By Victoria Rees (Drug Target Review) A new 3D model of the surface of the coronavirus COVID-19 has been released, to aid researchers in the development of a treatment.
news How do stem cells repair damage caused by a heart attack? 13 March 2020 | By Hannah Balfour (Drug Target Review) Researchers exploring how stem cells can be used discovered that cardiopoietic stem cells could repair in tissue in mouse models of heart attacks.
article Exploring future spinal cord injury therapies 11 March 2020 | By Hannah Balfour (Drug Target Review) Drug Target Review explores five of the latest research developments in the field of spinal cord injury (SCI) repair.
news Antibodies stimulate microglia to degrade Alzheimer’s amyloid plaques 11 March 2020 | By Hannah Balfour (Drug Target Review) A novel antibody has been shown to stimulate microglia to degrade amyloid plaques in a murine model of Alzheimer’s disease.
news TAZ gene therapy reverses Barth syndrome in mice 10 March 2020 | By Victoria Rees (Drug Target Review) Researchers have successfully treated cardiac dysfuntion in mice models of Barth syndrome by using a gene therapy to replace TAZ.
article Using virtual screening to identify coronavirus treatments 10 March 2020 | By Victoria Rees (Drug Target Review) Drug Target Review rounds up the latest updates on research into coronavirus treatments, focusing on virtual screening to find therapies for COVID-19.
news Novel compound to kill malaria parasites developed by researchers 6 March 2020 | By Victoria Rees (Drug Target Review) A collaborative team has developed a compound called WM382, which targets two crucial enzymes in the malaria parasite, effectively killing it.
news CAR T-cell receptors based on scorpion venom show efficacy in mice 5 March 2020 | By Victoria Rees (Drug Target Review) Combining the chlorotoxin peptide with conventional CAR structures, researchers have created a new CAR T cell therapy that has successfully combatted glioblastomas in mice.
news Blocking bacterial competence could prevent antibiotic resistance 4 March 2020 | By Hannah Balfour (Drug Target Review) Scientists suggest competence-blocking, ‘anti-evolution’ drugs could be administered alongside antibiotics to prolong the period before bacterial resistance emerges.
news ZT-1a compound could be an alternative to surgery for brain swelling 3 March 2020 | By Hannah Balfour (Drug Target Review) Rodent models of stroke and hydrocephalus treated with ZT-1a had reduced brain swelling, according to scientists.
article Rebalancing the immune system to treat autoimmune disease 2 March 2020 | By Hannah Balfour (Drug Target Review) Dr Nicolas Poirier reveals how immunotherapies can be designed to recalibrate the immune system for long-term maintenance of autoimmune remission.
news Inhaling stem cell secretome could be a more effective pulmonary fibrosis treatment 2 March 2020 | By Hannah Balfour (Drug Target Review) Rodent models of pulmonary fibrosis have been used to show that lung spheroid cell secretome therapy is as effective as stem cell secretome treatment.
news Metal-containing compounds could lead to new antibacterials 2 March 2020 | By Hannah Balfour (Drug Target Review) International collaboration has shown that compounds with metals in them show antibacterial activity against MRSA, E. coli and A. baumannii.
