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War On Cancer 2018: targeted therapies in oncology
War On Cancer 2018 discussed how cancer treatments have evolved over the last few decades, and looked at the future of cancer therapies...
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Therapeutics
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Muscular paralysis progression could be reduced using tamoxifen
Currently used for breast cancer, tamoxifen could be useful in preventing the progression of myotubular myopathy, a severe genetic disease...
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Inflammation inhibitor could be used to treat sepsis
An inhibitor that stops the action of OGG1 signals, could potentially be used as a treatment for life-threatening Acute Respiratory Distress Syndrome...
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PCSK9 inhibitors to treat high cholesterol
Low-density lipoprotein cholesterol could be treated by using synthetic DNA-encoded monoclonal antibodies to inhibit PCSK9...
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Inhibiting inflammation by blocking release of TNF alpha
Researchers at Karolinska Institutet collaborated with other researchers to develop a compound that prevents inflammation by blocking release of TNF alpha...
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Using anti-malaria drugs to slow tumour growth
Anti-malaria drugs, called chloroquines, target PPT1 from cancer cells, with researchers identifying how the drugs eliminate tumour growth in cancers...
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Precision neuroengineering reproduces brain-like functions in vitro
Using precision engineering, researchers form Japan and Spain have collaborated to show brain-like functions in vitro to advance medical research...
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Combination of imaging techniques views retina in unprecedented detail
Using two imaging techniques, adaptive optics and angiography, researchers have been able to view the retina in more detail than ever seen before...
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Vaccinia virus hijacks cellular movements to spread
To spread throughout the body, the vaccinia virus mimics the infected cells' own proteins enabling the cell to move around and spread...
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RIP1 kinase as a therapeutic target for pancreatic cancer
RIP1 has been shown to suppress the action of macrophages against the immune system and could be a potential therapeutic target for pancreatic cancer...
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Swarm of exosomes protect against inhaled bacteria
A swarm of billions of exosomes armed with proteins has been shown to assist in the fight against bacteria inhaled through the nose...
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Scientists test new anti-PD-L1 cancer vaccine against melanoma
An experimental cancer vaccine that boosts the immune system's ability to fight cancers could work in tandem with other cancer therapies to fight aggressive tumours, scientists have reported...
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Magnetically controlled thrombolytic passed preclinical trials
ITMO University scientists have used nanoparticles and magnetic waves to localise drug delivery in animal models, resulting in no side effects...
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Drug repurposing using off patent drugs as antifungals
Researchers have identified that Alexidine dihydrochloride can be used as a broad spectrum antifungal, and can also kill biofilms formed by these fungi...
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Gene responsible for hair loss discovered
The gene responsible for hair loss caused by the hypotrichosis simplex has been discovered by researchers at the University of Bonn...
