news
Link between TB and Parkinson’s disease identified
The mechanism our immune cells use to clear bacterial infections like tuberculosis might also be implicated in Parkinson's disease...
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Therapeutics
news
Cell types underlying schizophrenia identified
Scientists have identified the cell types underlying schizophrenia, the findings offer a roadmap for the development of new therapies to target the condition...
news
CHRNA2 receptor proteins may help fat cells burn energy
The same proteins that moderate nicotine dependence in the brain may be involved in regulating metabolism by acting directly on certain types of fat cells...
news
CRISPR used to destroy the regulatory genes of HIV
By destroying the regulatory genes of the AIDS virus HIV-1 using the genome editing system CRISPR/Cas9, researchers have succeeded in blocking the production of HIV-1 by infected cells...
news
Diabetes researchers find switch for fatty liver disease
Researchers have identified a key in the road for the way the liver deals with carbohydrates, fats and protein...
news
Charles River Laboratories announces extended relationship with The Michael J. Fox Foundation
Extension includes new project to phenotype Parkinson’s disease models and the continuation of LRRK2 research.
news
IL1RAP protein boosts multiple oncogenic pathways in AML
Researchers have discovered that a signalling protein elevated in patients with AML plays a much wider role in the disease than previously thought...
news
mEAK-7 gene could suggest path towards cancer therapies
Researchers have found mEAK-7 regulates the molecular process that dictates cell growth and human development...
news
Genomic analysis unravels complexities of the most common form of lymphoma
Genomic analysis has shown a better framework for understanding lymphoma’s many forms and will help to predict individual patient outcomes and guide personalised treatment.
news
FoxM1 gene provides promising target for pulmonary hypertension
The FoxM1 gene will drive the development of new drugs to reverse a process called vascular remodelling - a key feature in pulmonary hypertension...
news
Therapeutic RNA corrects splicing defect that causes familial dysautonomia
Scientists have identified a therapeutic RNA molecule that corrects the error in genetic processing that leads to familial dysautonomia...
news
Targeting telomerase as therapeutic strategy for melanoma
Combination therapy co-targeting the mitochondria enhances the antitumour effect of telomerase inhibition in NRAS-mutant melanoma.
webinar
Biomarker endpoints for Parkinson’s disease
26 April 2018 | By Charles River Laboratories
This webinar provides a comprehensive review of the validation data from established and novel animal models of Parkinson’s disease.
news
Antimicrobial therapy can prevent sepsis in pneumonia patients
Research sheds light on the initial phase of infectious disease and potential for prevention of pneumococcal septicaemia...
news
Chemogenetics provides hope for severe epilepsy
Researchers believe that they have found a method that in the future could help people suffering from epilepsy so severe that all current treatment is ineffective...
