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Kenpaullone protects from cisplatin-induced hearing loss
Researchers have discovered that inhibiting an enzyme called cyclin-dependent kinase 2 protects mice and rats from noise- or drug-induced hearing loss...
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Therapeutics
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Charles River Laboratories announces new tumour model compendium
The Compendium provides scientists an online resource to help design efficient in vitro and in vivo oncology research studies.
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Local environment plays key role in breast cancer progression
While studying the complex correlation between tissue stiffness and breast cancer development, researchers found that cancer cells tend to become more aggressive when the surrounding tissue stiffens...
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Ground-breaking research in continuous fight against AMR. Stay updated at the SMi’s event this March
The BBC recently reported on US's scientists discovery of a new family of antibiotics in soil samples. The natural compounds could be used to combat hard-to-treat infections, the team at Rockefeller University hopes.
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Lipid asymmetry plays key role in activating immune cells
Researchers have shown that by preventing loss of membrane asymmetry it's possible to control the immune response...
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MeXis gene may protect against heart disease
Scientists have identified a gene that may play a protective role in preventing heart disease...
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Explore next generation therapeutics and ATMPS in May
The 13th annual World Advanced Therapies & Regenerative Medicine Congress brings together 1000+ attendees and explores the rapidly developing world of next generation therapeutics and ATMPS.
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Osimertinib resistance explained by computer simulations
Scientists have used molecular simulations to understand the resistance to osimertinib - an anticancer drug used to treat types of lung cancer...
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PGEC-derived organoids produce stable gut and liver tissue
Researchers have bioengineered organs that are free from the risk of tumour growth--and of sufficient volume and size for viable transplant...
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Scientists target glioma cancer stem cells which could improve patient survival
Dartmouth scientists have successfully uncovered a therapeutic approach that targets aggressive brain cancer stem cells and could lead to improved patient survival.
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SMi’s 9th annual RNA Therapeutics conference will take place in just 2 weeks!
Presenting issues and real-life examples within the RNA space, SMi welcome insights and discussions into new technologies for single-stranded RNA, epigenetics to develop first-in class drugs in oncology, patenting RNA Therapeutics and exploring the latest developments in delivery systems, including Exosomes and Nanocomplexes. Read on for your exclusive discount to…
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New to 2018: The role of artificial intelligence in drug discovery
SMi Reports: SMi’s 2nd annual Drug Discovery conference, taking place in London on 21 and 22 March 2018, will discuss the role of artificial intelligence in drug discovery.
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Elimination of c-Raf kinase induces regression of advanced lung tumours
A study has shown how the elimination of the c-Raf kinase by genetic manipulation causes the regression of Kras oncogene-driven advanced lung tumours...
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The highlights to look forward to at SMi Groups Controlled Release Delivery Conference in March 2018
Our agenda is packed with keynote addresses, expert speakers, informative content and senior figures from within the industry…read on to find out more…
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Discovery into cells’ energy supply could lead to targeted cancer treatment
Scientists have made a significant breakthrough in understanding how the molecular machines that produce key proteins are cleaned and maintained. ..
