reference
New immune targets to improve survival from sepsis
References for ‘New immune targets to improve survival from sepsis’, in Drug Target Review Issue 2 2022.
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Translational Science
webinar
Improving Huntington’s disease drug discovery with new reproducible disease models
27 May 2022 | By bit.bio
This webinar explores how a new generation of reproducible and scalable human cell models are being utilised for drug discovery in Huntington’s disease.
news
A three-dimensional model for rare neuromuscular disorders
Scientists have created a tiny, bioengineered 3D model that mimics the biology of chronic inflammatory demyelinating polyneuropathy and multifocal motor neuropathy, a pair of rare, devastating neuromuscular diseases.
news
Novel technique to rapidly find prostate cancer drugs
A new screening assay could be used to identify new drugs to treat resistant forms of prostate cancer.
news
New genetic model of Down’s syndrome developed in rats
Scientists have created what they believe is the first rat model of Down’s syndrome. The animal model shares features with human Down’s syndrome, which will allow for efficient testing of new therapies.
news
“Monumental” step in using human iPSCs towards treating complication of diabetes
A new study led by the Indiana University School of Medicine showed human induced pluripotent stem cells can improve visual acuity, vascular health and other complications related to type 2 diabetes.
article
Pre-clinical models of endometriosis and their value for translational research
In this exclusive Q&A, Dr Paulina Nunez-Badinez, Scientific Researcher at Bayer AG, discusses pre-clinical research of pain related to endometriosis and why there is a lack of research around this area.
news
Cannabidiol analogue could enhance chemotherapy by preventing neuropathic pain
A new study has revealed a cannabidiol analogue can possibly prevent neuropathic pain induced by chemotherapy, as well as being beneficial against cancer.
news
New pre-clinical study demonstrates innovative approach to treating brain diseases
Researchers have been able to slow down the progression of glioblastoma in mice, the most common adult brain cancer.
news
Bone marrow stem cell transfusions show promise as potential treatment for sepsis
New research has shown that one-time infusion of stem cells from bone marrow improves the survival of mice with sepsis.
news
Tweaked bacteria genes activate heart cells in mice
Researchers have shown that engineered bacterial genes coding for sodium ion channels could lead to novel gene therapies for electrical heart diseases.
news
Researchers identify potential drugs to reduce COVID-19 mortalities
Researchers have established a list of compounds that effect cytokine storms that could reduce mortality in COVID-19 patients.
news
Avacta selects chemotherapy drug candidate for pre-clinical development
Avacta Group announced that the chemotherapy candidate AVA3996 will be developed with a view to a first-in-human clinical trial beginning in 2023.
news
Novel nanotherapy offers hope for potential treatment of type 1 diabetes
Researchers have developed rapamycin-loaded nanocarriers capable of targeting cells related to pancreatic islet transplants without suppressing wider immune responses.
news
Experimental mRNA HIV vaccine shows promise in pre-clinical studies
A new potential mRNA vaccine that delivers instructions for making two key HIV proteins has been tested in mice and rhesus macaques.
