news Dual antibodies effective against SARS-CoV-2 variants in animal study 22 June 2021 | By Victoria Rees (Drug Target Review) In mice and hamsters, therapies made from two antibodies were found to be mostly effective against a range of SARS-CoV-2 variants.
news Nanodecoy therapy neutralises SARS-CoV-2 in macaques 18 June 2021 | By Victoria Rees (Drug Target Review) Lung spheroid cells can act as nanodecoys for the SARS-CoV-2 Spike protein to bind to, according to a new pre-clinical study.
news Potential ovarian cancer treatment proves effective in pre-clinical studies 14 June 2021 | By Victoria Rees (Drug Target Review) A new radiopharmaceutical compound has shown success at treating ovarian cancer in mice and in vitro studies.
news Senolytic drugs reduce COVID-19 symptoms in mice, study shows 9 June 2021 | By Victoria Rees (Drug Target Review) In pre-clinical studies, senolytic drugs were found to reduce inflammation and death from COVID-19 in older mice.
news Tiny implant cures diabetes in mice without triggering immune response 7 June 2021 | By Victoria Rees (Drug Target Review) Scientists have developed an implant that releases insulin-secreting cells which has shown success at treating diabetes in mice.
news Analogue of psychedelic ibogaine reverses effects of stress in mice 26 May 2021 | By Victoria Rees (Drug Target Review) Tabernanthalog (TBG), similar to the psychedelic drug ibogaine, corrected stress-induced behavioural deficits in mice.
news Gene therapy in Alzheimer’s mouse model preserves learning and memory 5 May 2021 | By Victoria Rees (Drug Target Review) A new gene therapy that introduced SynCav1 to the brains of Alzheimer's mouse models was shown to preserve neuronal and synaptic plasticity.
news Hepatitis C drugs shown to boost remdesivir’s activity against SARS-CoV-2 28 April 2021 | By Victoria Rees (Drug Target Review) Four hepatitis C drugs have demonstrated promise as boosters to increase the efficacy of remdesivir against SARS-CoV-2 by as much as tenfold.
news Inhibiting METTL3 enzyme combats acute myeloid leukaemia in mice 27 April 2021 | By Victoria Rees (Drug Target Review) Scientists have developed a drug called STM2457 which inhibits a key enzyme involved in acute myeloid leukaemia.
news Experimental drug shown to reverse effects of Alzheimer’s in mice 23 April 2021 | By Victoria Rees (Drug Target Review) Oral doses of a new drug named CA administered to mouse models led to improvements in Alzheimer's disease, including memory.
news Stem cell therapy repairs damage from dementia in mouse brains 22 April 2021 | By Victoria Rees (Drug Target Review) Researchers have developed a stem cell therapy that could treat the damage caused by dementia by launching a repair response.
article Targeting TNF to treat Dupuytren’s disease, frozen shoulder and POCD 20 April 2021 | By Dr James Woody (180 Life Sciences) Dr James Woody discusses off-patent indications for anti-TNF to address unmet patient needs in pain, inflammation and beyond.
news MK-4482 antiviral effective against SARS-CoV-2 in hamster study 19 April 2021 | By Victoria Rees (Drug Target Review) The drug MK-4482 decreased viral levels in the lungs of hamsters treated for SARS-CoV-2 infection, researchers have shown.
news New gene therapy could preserve vision in retinitis pigmentosa patients 14 April 2021 | By Victoria Rees (Drug Target Review) Delivering Txnip to mice with retinitis pigmentosa was an effective treatment, making this approach a potential gene therapy for the disease.
news β-cell regeneration discovery could pave way for diabetes treatments 16 February 2021 | By Victoria Rees (Drug Target Review) A key process in β-cell regeneration has been discovered by researchers who say this could lead to improved treatments for diabetes.
