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Translational Science
The National Institutes of Health announce Biobanking Medical Project
SMi Reports: The National Institutes of Health announce one of the most ambitious medical projects in biobanking, which will commence this spring.
Expert view: Laboratory informatics software – the top challenges
A look back, and forward, at the key trends within laboratory informatics.
Case Study: Characterisation of hiPSCs by Phenotypic Screening
Case study detailing a simple, highly reproducible phenotypic screen to characterise human induced pluripotent stem cells...
Operetta CLS High-Content Analysis System
6 February 2018 | By PerkinElmer
Operetta CLS is a high-content cell analysis system featuring a unique combination of technologies to deliver high speed, sensitivity, and resolution...
JANUS® G3 automated workstation
26 January 2018 | By PerkinElmer
The JANUS G3 automated workstation offers multiple pipetting technologies on a single instrument platform.
Whitepaper: Phenotypic drug discovery with high content screening
Reasons for phenotypic vs. target based drug discovery strategies, challenges of and maximising return of phenotypic assays.
Application note: Distinguishing cell types by phenotypic profiling
Describing how a single nuclear stain can enable phenotypic profiling for new and additional perspectives on assays at no extra cost.
Tech note: Benefits of water immersion lenses for HCS
Water immersion lenses provide: brighter images from HCS samples; faster and gentler imaging; higher quality images from both 2D and 3D samples.
Webinar: Phenotypic assays for CNS disease drug discovery
21 September 2017 | By Charles River Laboratories
In this webinar, we highlight in vitro models and phenotypic assays to discover and validate novel targets and promising lead molecules...
Expert view: Single-cell sequencing in basic research and clinical applications
Next-generation sequencing (NGS) has greatly increased our understanding of biological phenomena and human disease. In particular, single-cell sequencing is one of the fastest-growing applications...
Cognitive Phenotypes in MS Mouse Models
22 June 2017 | By Charles River Laboratories
40-65% of MS patients have cognitive impairment and touchscreen testing in animal models is a new method to test cognitive issues in MS animal models...
Paper: Acquisition and reversal of visual learning in CVN mice
Peer-reviewed paper on how touchscreen testing is a translational tool to assess cognitive function in a mouse model of Alzheimer’s disease...
Review: Protein misfolding in neurodegenerative diseases
Peer-reviewed publication on new strategies to target misfolded protein aggregates at various steps of protein production and processing...