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ON-DEMAND By DiscoverX
In this webinar, DiscoverX Corporation discuss three negative allosteric modulators of metabotropic glutamate receptors, developed by Pfizer, which recently failed in preclinical development due to delayed type IV skin hypersensitivity observed in non-human primates...
ON-DEMAND By DiscoverX
The goal of this webinar is to illustrate how knowledge of MrgX2 activity across a panel of mammalian species can be integrated into drug development to influence choice of compound, species model and dosing regimen...
ON-DEMAND By Charles River Laboratories
40-65% of MS patients have cognitive impairment and touchscreen testing in animal models is a new method to test cognitive issues in MS animal models...
ON-DEMAND By PerkinElmer
In this webinar, PerkinElmer and AMRI will present a case study wherein high-performance computing (HPC) was leveraged for enhanced performance in image and data analysis of High Content Screening experiments...
ON-DEMAND By Charles River
This webinar reviews standard neuropathic pain models and readouts and will include fine motor kinematic analysis to highlight gait changes...
ON-DEMAND By Charles River
Discover how their multidisciplinary approach to hit ID, design and synthesis of novel chemical templates and development of targeted in vitro and in vivo assays resulted in the nomination of the first development candidate in just over two years...
ON-DEMAND By Charles River
This webinar discusses our newly validated acute and inflammatory in vivo pain models, including information on how they were validated and how they can be used to test new pain treatment compounds, eventually leading to clinical translation...
ON-DEMAND By Charles River
This webinar explores neurological ion channel therapeutic and liability targets, featuring four subtypes of NMDA receptors. We also discuss the rationale and options for assessment of therapeutic compounds on panels of CNS ion channels for evaluating their risk for CNS liabilities...
ON-DEMAND By Charles River
In this webinar, Charles River discuss the utilisation of CRISPR/Cas9 technology in drug discovery, with an emphasis on generation of in vitro models for high-throughput screening, and creating new mouse models...
ON-DEMAND By Bruker
This webinar discusses a new MALDI Time-of-flight (TOF) Mass Spectrometer, designed for ultra-fast label-free screening of biochemical assays...
ON-DEMAND By Charles River
This webinar details a successful new strategy to identify small molecule therapies to treat protein-destabilizing monogenic disorders...
ON-DEMAND By Charles River
This webinar details a novel automated and high-precision system to successfully analyze early changes in muscular or neuronal function in disease models...
ON-DEMAND By Intellicyt
This webinar highlights the use of the iQue Screener for high-throughput screening of stem cells, small molecules and CRISPR functional screening, presented by David Sykes, M.D., Ph.D., Researcher from Massachusetts General Hospital and Thibault Jonckheere, CEO and Séverine Giltaire, Senior Scientist from ImmunXperts...
ON-DEMAND By Charles River
This webinar highlights imaging as well as cognitive and physiological testing of AD models...
ON-DEMAND By IntelliCyt Corporation
In this webinar, Belen Ybarrondo, Ph.D and Thomas Duensing, Ph.D discuss the need for robust high content tools for current immunotherapeutic approaches, and how IntelliCyt's iQue Screener PLUS can give functional efficacy of immuno-oncology therapies...
