How pure consistent and functional lower motor neurons can be precision reprogrammed from iPSCs for motor neuron disease research and drug discovery.
The development of motor neuron disease (MND) therapeutics is hampered by the limited translatability of existing preclinical animal models and the lack of reliable, consistent in vitro MND models. In this scientific poster, discover ioMotor Neurons: scalable, consistent, and functional human iPSC-derived motor neurons precision reprogrammed with opti-ox™. Explore functional MEA data, and RNA-seq data showing the cell’s applicability to pre-clinical in vitro drug development workflows.
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