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From the B-27 Plus Neuronal Culture System to fluorescent probes for cell analysis. Publication history of B-27 supplements demonstrates that researchers are expanding its use, far beyond the long-term culture of rat hippocampal and cortical neurons.
HCA platforms automate image capture and data analysis, giving researchers the sample sizes and precise quantitation tools required for research.
Ensure reproducibility with TruBIOME™ - the unique approach to generating research model colonies, which allows you complete control over their microbiome, from conception to cohort delivery.
High-content analysis app note: Phenotypic fingerprint of cellular function following gene editing by high-throughput imaging acquisition and analysis.
High-content analysis: monitoring neurite morphology and synapse formation in primary neurons for neurotoxicity assessments and drug screening.
Learn more about an emerging high-throughput method for identifying and isolating rare cells secreting antigen-specific antibodies.
Learn everything you need to know about the most widely-used mouse in biomedical research with this free whitepaper.
Learn how the continued development of CRISPR gene editing technologies opens fresh possibilities for in vivo model design.
Find out how to streamline Cell Line Development by identifying high-producing clones with monoclonality assurance in one day.
SB Drug Discovery shows the validation of fluorescence and automated electrophysiology assays designed to assess agonists, antagonists and allosteric modulators of these receptors, culminating in a high-throughput electrophysiology assay suited to assessing multiple GABAA receptor subtypes on a single assay plate.
There is substantial interest in the scientific community in using human induced pluripotent stem cell (hiPSC)-derived neural cells to study basic mechanisms of brain development, neuronal function, and drug-induced effects. In vitro-generated brain organoids are promising models, because they show a remarkable degree of maturation and can be kept in…
This technical note demonstrates the feasibility of using the Thermo Scientific™Fluoroskan™ or Fluoroskan FL instruments with the Invitrogen™ Quant-iT™ dsDNAhigh-sensitivity assays. Sensitive and specific quantification of double-stranded DNA is carried out in microplate format. This is part of a series of technical notes aiming to help customers choose the best…
Development and production of biopharmaceuticals is complex. Even minor impurities, or changes in attributes such as glycosylation or charge heterogeneity, can have a profound impact on the safety and efficacy of the final product. Traditionally, multiple analytical techniques have been required to assess the full range of biopharmaceutical product attributes.…
Every day scientists are working to discover and develop new therapies and treatments to change the lives of patients suffering from serious and debilitating illnesses. Amgen Inc. has made it a priority to unlock the potential of biology to discover, develop, manufacture, and deliver innovative therapeutics to patients.
With breakthroughs in molecular engineering and antibody humanisation, monoclonal antibodies (mAb) are one of the fastest-growing classes of biopharmaceuticals for multiple clinical indications including cancer, cardiovascular disease, autoimmune disorders and infectious disease. Most therapeutic antibody candidates are initially generated using hybridoma technology or primary B-cell screening after antigen immunisation.
